Results 151 to 160 of about 47,863 (285)

Endocannabinoid and nitric oxide systems of the hypothalamic paraventricular nucleus mediate effects of NPY on energy expenditure

Molecular Metabolism, 2018
Objective: Neuropeptide Y (NPY) is one of the most potent orexigenic peptides. The hypothalamic paraventricular nucleus (PVN) is a major locus where NPY exerts its effects on energy homeostasis.
Zoltán Péterfi, Imre Farkas, Raphael G.P. Denis, Erzsébet Farkas, Motokazu Uchigashima, Tamás Füzesi, Masahiko Watanabe, Ronald M. Lechan, Zsolt Liposits, Serge Luquet, Csaba Fekete   +10 more
doaj  

The transcriptomic signature of DEPDC5 KO induced mTOR hyperactivation in human neurons and its response to rapamycin treatment

Epilepsia, EarlyView.
Abstract Objective Mutations of the DEP Domain Containing 5 gene (DEPDC5), a mechanistic Target of Rapamycin (mTOR) inhibitor involved in amino acid sensing, are associated with neurological diseases such as epilepsy and/or autism spectrum disorder (ASD). Loss of DEPDC5 impacts early neuronal development via mTOR hyperactivity.
Mattson S. O. Jones, Silvia Lindlar, Johannes Ludwig, Regina Waltes, Afsheen Kumar, Sophie v. Brauchitsch, Andrea Rossi, Evelyn Ullrich, Stefan Momma, Christine M. Freitag, Jasmin K. Hefendehl, Karl Martin Klein, Felix Rosenow, Denise Haslinger, Andreas G. Chiocchetti   +14 more
wiley   +1 more source

Overexpression of the short isoform of the dopamine D2 receptor causes diet‐induced obesity and hyperglycemia in mice

Journal of Neuroendocrinology, EarlyView.
Alterations in the expression levels of D2S and D2L resulted in obesity and metabolic syndrome such as abdominal fat accumulation and hyperglycemia in D2L KO mice fed with a high‐fat diet, compared to WT mice. This may be partly due to increased food intake.
Hanna Gonzalez, Lei Cheng, Qing Chang, Paul E. Gold, Diego Perez‐Tilve, YanYan Wang   +5 more
wiley   +1 more source

The effect of moxonidine on feeding and body fat in obese Zucker rats: role of hypothalamic NPY neurones [PDF]

, 1999
Bing Chen, Peter King, Lucy Pickavance, Michael J. Brown, Dieter Ziegler, Elbert C. Kaan, Gareth Williams   +6 more
openalex   +1 more source

Disrupted circadian rhythms and opioid‐mediated adverse effects: Bidirectional relationship and putative mechanisms

Journal of Neuroendocrinology, EarlyView.
Abstract Recent studies have shown a link between disrupted circadian rhythms and the development of chronic opioid‐induced negative effects. Both animal and human studies show a significant bidirectional relationship between the circadian system and opioid effects.
Nasrin Mehranfard, Maedeh Ghasemi, Ehsan Saboory   +2 more
wiley   +1 more source

NPY mediates ATP-induced neuroproliferation in adult mouse olfactory epithelium

Neurobiology of Disease, 2010
In the CNS, ATP is released upon injury and promotes neuroproliferation via purinergic receptors. In the olfactory epithelium, ATP promotes the synthesis and release of neurotrophic factor NPY in neonates and induces neuroproliferation in neonatal and ...
Cuihong Jia, Colleen Cosgrove Hegg
doaj  

Plasma Neuropeptide Y (NPY) Increases in Humans in Response to the α2 Antagonist Yohimbine [PDF]

, 1998
Ann M. Rasmusson, M.D Steven M Southwick, Marsha Hauger, M.D Dennis S Charney   +3 more
openalex   +1 more source

The Strongly Asynchronous Massive Access Channel

, 2018
This paper considers a Strongly Asynchronous and Slotted Massive Access Channel (SAS-MAC) where $K_n:=e^{n\nu}$ different users transmit a randomly selected message among $M_n:=e^{nR}$ ones within a strong asynchronous window of length $A_n:=e^{n\alpha}$
Devroye, Natasha, Shahi, Sara, Tuninetti, Daniela   +2 more
core   +2 more sources

Stress alters hypothalamic gene expression in adolescent male Golden hamsters

Journal of Neuroendocrinology, EarlyView.
Abstract In Golden hamsters (Mesocricetus auratus), a two‐week exposure to chronic social stress in adolescence causes acceleration of agonistic behavior, enhanced adult aggression, impaired waiting impulsivity, and higher food intake, body fat, and long‐term increased body weight.
Kevin M. Moran, Tyler M. Milewski, James P. Curley, Yvon Delville   +3 more
wiley   +1 more source

α₂‐Adrenoceptor and NPY receptor‐mediated contractions of porcine isolated blood vessels: evidence for involvement of the vascular endothelium [PDF]

, 1999
R. E. Roberts, Dave Kendal, V.G. Wilson
openalex   +1 more source