Neuropeptide Y is produced by adipose tissue macrophages and regulates obesity-induced inflammation. [PDF]
PLoS ONE, 2013 Neuropeptide Y (NPY) is induced in peripheral tissues such as adipose tissue with obesity. The mechanism and function of NPY induction in fat are unclear.
Kanakadurga Singer +8 more
doaj +1 more source
Depressor Effect of Intrathecal Neuropeptide Y (NPY) Is Mediated by Y2 Subtype of NPY Receptors
Journal of Cardiovascular Pharmacology, 1993 The effect of intrathecal administration of neuropeptide Y (NPY), NPY COOH-terminal fragments as well as an NPY Y1 receptor ligand on arterial blood pressure (ABP) of anesthetized rat was studied. NPY and all NPY COOH-terminal fragments tested (NPY11-36, NPY14-36 and NPY18-36), believed to act through Y2 receptors produced a dose-related depressor ...
Xiaoli Chen, Thomas C. Westfall
openalex +4 more sources
Placental Neuropeptide Y (NPY) and NPY receptors expressions and serum NPY levels in preeclampsia [PDF]
Experimental Biology and Medicine, 2019 Neuropeptide Y (NPY) has been reported as a vasoconstrictive substance that might be associated with preeclampsia. NPY mediates different effects via its specific NPY receptors. NPY action via Y1 receptor (Y1R) and/or Y5 receptor (Y5R) induces vascular smooth muscle cells proliferation while it is implicated in angiogenesis via Y2 receptor (Y2R) and ...
Roongrit Klinjampa +7 more
openaire +3 more sources
Platelet lysate-derived neuropeptide y influences migration and angiogenesis of human adipose tissue-derived stromal cells [PDF]
, 2018 Neuropeptide Y (NPY), a powerful neurotransmitter of the central nervous system, is a key regulator of angiogenesis and biology of adipose depots. Intriguingly, its peripheral vascular and angiogenic powerful activity is strictly associated to platelets,
Bordin, Antonella +13 more
core +2 more sources
NPY and NPY receptors in airway structural and inflammatory cells in allergic asthma [PDF]
Experimental and Molecular Pathology, 2013 Neuropeptide Y (NPY) level is elevated in allergic asthmatic airways and activation of NPY receptor-1 (NPY-Y1) on antigen-presenting cells (APCs) is essential for T cell priming. Paradoxically, NPY-Y1 modulates hyper-responsiveness in T cells, suggesting a bimodal role for NPY in APCs and T cells.
Toluwalope O. Makinde +2 more
openaire +2 more sources
Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]
, 2013 Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Ferenczi, Szilamér +6 more
core +9 more sources
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on NPY (neuropeptide Y), with data on DNA, on the protein encoded, and where the gene is implicated.
M. Ruscica, E. Dozio, P. Magni
openaire +4 more sources
What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands [PDF]
, 2019 Dipeptidyl peptidase 4 (DPP4) is an exopeptidase found either on cell surfaces where it is highly regulated in terms of its expression and surface availability (CD26) or in a free/circulating soluble constitutively available and intrinsically active form.
Aguilar-Pérez, Alexandra +13 more
core +1 more source
Sustained NPY signaling enables AgRP neurons to drive feeding
eLife, 2019 Artificial stimulation of Agouti-Related Peptide (AgRP) neurons promotes intense food consumption, yet paradoxically during natural behavior these cells are inhibited before feeding begins.
Yiming Chen +6 more
semanticscholar +1 more source
Glial-derived neurotrophic factor modulates enteric neuronal survival and proliferation through neuropeptide Y. [PDF]
, 2006 BACKGROUND & AIMS: Glial-derived neurotrophic factor (GDNF) promotes the survival and proliferation of enteric neurons. Neuropeptide Y (NPY) is an important peptide regulating gastrointestinal motility.
Anitha, M. +6 more
core +2 more sources