Noncoding RNAs, Vital Players in Breast Cancer Metastasis. [PDF]
Kang Y +5 more
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Genome sequencing provides high diagnostic yield and new etiological insights for intellectual disability and developmental delay. [PDF]
Hamanaka K +66 more
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Editorial: Cellular senescence in aging-related diseases: mechanisms and therapeutic targets. [PDF]
Zhou J, Wang H, Zhu F.
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The Natural Course of Bosch-Boonstra-Schaaf Optic Atrophy Syndrome. [PDF]
Valentin I +4 more
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Nr2f1 enhancers have distinct functions in controlling Nr2f1 expression during cortical development
There is evidence that transcription factor (TF) encoding genes, which temporally control development in multiple cell types, can have tens of enhancers that regulate their expression.
Athena R Ypsilanti +2 more
exaly +6 more sources
NR2F1 regulates regional progenitor dynamics in the mouse neocortex and cortical gyrification in BBSOAS patients [PDF]
The relationships between impaired cortical development and consequent malformations in neurodevelopmental disorders, as well as the genes implicated in these processes, are not fully elucidated to date.
Michele Bertacchi +2 more
exaly +7 more sources
COUP-TFI/Nr2f1 Orchestrates Intrinsic Neuronal Activity during Development of the Somatosensory Cortex [PDF]
International audienceThe formation of functional cortical maps in the cerebral cortex results from a timely regulated interaction between intrinsic genetic mechanisms and electrical activity.
Isabel Del Pino +2 more
exaly +8 more sources
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NR2F1-AS1: A Functional Long Noncoding RNA in Tumorigenesis
Current Medicinal Chemistry, 2023Background: NR2F1-AS1 is a long non-coding RNA (lnc RNA) that is involved in different biological processes. It plays an integral role in the pathophysiology of human diseases, especially tumorigenesis and progression. Therefore, it may be a promising target for numerous tumor biotherapeutics.
Chengfu Yuan, Jiahui Hu, Jingjie Yang
exaly +3 more sources
Emerging evidence has uncovered the extremely important roles of long noncoding RNAs (lncRNAs) in the progression of malignant tumors which includes numerous processes of gene regulation. LncRNA NR2F1-AS1 has been confirmed to have close correlation with the tumorigenesis of diverse cancers.
Yaowen Zhang +2 more
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