Results 101 to 110 of about 9,804 (228)
Foot-and-mouth disease virus genome replication is unaffected by inhibition of type III phosphatidylinositol-4-kinases [PDF]
, 2016 Foot-and-mouth disease virus (FMDV) causes economically-damaging infections of cloven-hooved animals, with outbreaks resulting in large financial losses to the agricultural industry.
Belsham +9 more
core +1 more source
MicrobiologyOpen, Volume 14, Issue 4, August 2025.Galla chinensis is an eco‐friendly and effective alternative to traditional antibiotics for combating multidrug resistance. ABSTRACT Carbapenemase‐producing Enterobacteriaceae (CPE) represents a significant global public health concern, largely driven by factors including misuse of antibiotics and their inappropriate use in livestock.
MinHui Miao +7 more
wiley +1 more source
Annals of Hepatology, 2017 Introduction: Recurrence of HCV infection in patients with chronic hepatitis C virus (HCV) at the time of liver transplantation is nearly universal and reduces the likelihood of graft and patient survival.
Eric M. Yoshida +19 more
doaj +1 more source
Overview of hepatitis C infection, molecular biology, and new treatment
Journal of Infection and Public Health, 2020 The World Health Organization estimates that 71 million people worldwide have chronic hepatitis C viral infection. A major challenge is overall lack of public awareness of hepatitis C, particularly among infected people of their infection status. Chronic
Ali A. Rabaan +6 more
doaj +1 more source
Hepatitis C Virus and Hepatocarcinogenesis [PDF]
, 2012 Hepatitis C virus (HCV) is an RNA virus that is unable to integrate into the host genome. However, its proteins interact with various host proteins and induce host responses.
Chung, Raymond Taeyong +2 more
core +2 more sources
Small molecule inhibitors of the hepatitis C virus-encoded NS5A protein
Virus Research, 2012 Hepatitis C virus (HCV) is a modern-day pandemic; 2-3% of the world's population are thought to be infected with the virus and are subsequently at risk of developing end-stage liver diseases. The traditional standard of care (SOC) for HCV-infected patients has been limited to a regimen of pegylated-interferon alpha (pegIFN) and ribavirin; displaying ...
Oscar, Belda, Paul, Targett-Adams
openaire +2 more sources
Dynamic protein interactions probed by NMR spectroscopy
Bulletin of the Korean Chemical Society, Volume 46, Issue 7, Page 680-690, July 2025.Abstract Dynamic protein–protein interactions are essential for diverse cellular processes but often evade structural characterization due to their transient, heterogeneous, and disordered nature. This review focuses on how nuclear magnetic resonance (NMR) spectroscopy can provide detailed, residue‐level insights into these complex interactions.
Jaeseok Lee, Jung Ho Lee
wiley +1 more source
Pharmacokinetic interactions between simeprevir and ledipasvir in treatment naive hepatitis C virus genotype 1-Infected patients without cirrhosis treated with a simeprevir-sofosbuvir-ledipasvir regimen [PDF]
, 2017 Interactions between simeprevir (hepatitis C virus [HCV] NS3/4A protease inhibitor) and ledipasvir (HCV NS5A replication complex inhibitor) were investigated in treatment-naive HCV genotype 1-infected patients without cirrhosis, treated with simeprevir ...
Beumont, Maria +12 more
core +2 more sources
Profile of sofosbuvir/velpatasvir/voxilaprevir in the treatment of hepatitis C
Infection and Drug Resistance, 2019 Lindsey M Childs-Kean, Natalie A Brumwell, Emma F LodlDepartment of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL, USAAbstract: The treatment of chronic hepatitis C has been revolutionized with the
Childs-Kean LM, Brumwell NA, Lodl EF
doaj
Viruses, 2015 Sustained virological response (SVR) rates have increased dramatically following the approval of direct acting antiviral (DAA) therapies. While individual DAAs have a low barrier to resistance, most patients can be successfully treated using DAA ...
Kazuaki Chayama, C. Nelson Hayes
doaj +1 more source