Results 91 to 100 of about 9,413 (173)

Active-site Molecular docking of Nigellidine to nucleocapsid/Nsp2/Nsp3/MPro of COVID-19 and to human IL1R and TNFR1/2 may stop viral-growth/cytokine-flood, and the drug source Nigella sativa (black cumin) seeds show potent antioxidant role in experimental rats. [PDF]

, 2020
Smarajit Maiti, Amrita Banerjee, Aarifa Nazmeen, Mehak Kanwar, Shilpa Das   +4 more
openalex   +1 more source

Isothermal Titration Calorimetry of fragments and Nsp3 macrodomain of SARS-CoV-2

, 2021
Roberto Efraín Díaz, James S. Fraser
openalex   +2 more sources

Oligomeric assembly of the C-terminal and transmembrane region of SARS-CoV-2 nsp3

Journal of Virology
ABSTRACT As for all single-stranded, positive-sense RNA (+RNA) viruses, intracellular RNA synthesis relies on extensive remodeling of host cell membranes that leads to the formation of specialized structures.
Babot, Marion, Boulard, Yves, Agouda, Samira, Pieri, Laura, Fieulaine, Sonia, Bressanelli, Stéphane, Gervais, Virginie   +6 more
openaire   +3 more sources

SARS-CoV-2 nsp3 C-terminal region: Conserved beyond coronavirus with potential role in DMV pore formation [PDF]

Yulia Pustovalova, Alexandra Pozhidaeva, Jeffrey C. Hoch   +2 more
openalex   +1 more source

SARS-CoV-2 nsp3 macrodomain His-tagged expression and purification protocol for assay v2 [PDF]

Korvus Wang, M. Fairhead, Eleanor Williams   +2 more
openalex   +2 more sources

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

, 2021
M. Schuller, G.J. Correy, Stefan Gahbauer, D. Fearon, Taiasean Wu, Roberto Efraín Díaz, I.D. Young, Luan Carvalho Martins, Dominique H. Smith, Ursula Schulze‐Gahmen, Tristan W. Owens, Ishan Deshpande, Gregory E. Merz, Aye C. Thwin, J.T. Biel, Jessica K. Peters, Michelle Moritz, Nadia Herrera, Huong T. Kratochvil, A. Aimon, James M. Bennett, J. Brandão-Neto, Aina E. Cohen, Alexandre Dias, A. Douangamath, Louise Dunnett, Oleg Fedorov, Matteo P. Ferla, Martin R. Fuchs, T.J. Gorrie-Stone, James M. Holton, Michael G. Johnson, T. Krojer, G. Meigs, A.J. Powell, J.G.M. Rack, V.L. Rangel, Silvia Russi, R. Skyner, Clyde A. Smith, Alexei S. Soares, Jennifer L. Wierman, Kang Zhu, Peter O’Brien, Natalia Jura, Alan Ashworth, John J. Irwin, Michael C. Thompson, Jason E. Gestwicki, F. von Delft, Brian K. Shoichet, James S. Fraser, Ivan Ahel   +52 more
openalex   +1 more source

Frequent occurrence of mutations in nsp3 and nsp4 of SARS-CoV-2, presumably caused by the inhaled asthma drug ciclesonide

, 2022
Akihiro Doi, Yuriko Tomita, Hiyori Okura, Shutoku Matsuyama   +3 more
openalex   +1 more source

Docking fragment screen against Nsp3 macrodomain of SARS-CoV-2

, 2021
Stefan Gahbauer, Brian K. Shoichet
openalex   +1 more source

Hypervariable Domain of Eastern Equine Encephalitis Virus nsP3 Redundantly Utilizes Multiple Cellular Proteins for Replication Complex Assembly [PDF]

, 2017
Ilya Frolov, Dal‐Young Kim, Maryna Akhrymuk, James A. Mobley, Elena I. Frolova   +4 more
openalex   +1 more source

Both ADP-Ribosyl-Binding and Hydrolase Activities of the Alphavirus nsP3 Macrodomain Affect Neurovirulence in Mice [PDF]

, 2020
Rachy Abraham, Robert Lyle McPherson, Morgan Dasovich, Mohsen Badiee, Anthony K. L. Leung, Diane E. Griffin   +5 more
openalex   +1 more source