Results 111 to 120 of about 14,750 (231)
Directed Irradiation Synthesis as an Advanced Plasma Technology for Surface Modification to Activate Porous and “as-received” Titanium Surfaces [PDF]
, 2019 For the design of smart titanium implants, it is essential to balance the surface properties without any detrimental effect on the bulk properties of the material.
Allain, Jean Paul +10 more
core +1 more source
Advanced Science, Volume 12, Issue 38, October 13, 2025.Self‐amplifying (saRNA), linear (linRNA), and circular (circRNA) mRNAs are compared under standardized conditions using lipid nanoparticles (LNPs) and pABOL polymer. saRNA achieved superior expression, while linRNA and circRNA performance varied based on untranslated region elements and delivery method.
Irafasha C. Casmil +12 more
wiley +1 more source
READDI protocol: Crystallisation of CHIKV nsP3 macrodomain v2
The crystallization protocol and buffer conditions used to obtain reproducible Chikungunya Virus NS3 macrodomain crystals suitable for XChem fragment screening.
Jasmin Aschenbrenner +4 more
openaire +1 more source
Functions of Alphavirus Macrodomain-containing protein nsP3 [PDF]
, 2011 Alphaviruses are positive strand RNA viruses that replicate in association with cellular membranes. The viral RNA replication complex consists of four non-structural proteins nsP1-nsP4 which are essential for viral replication.
Neuvonen, Maarit
core
A duplex real-time reverse transcriptase polymerase chain reaction assay for detecting western equine and eastern equine encephalitis viruses [PDF]
, 2010 In order to establish an accurate, ready-to-use assay for simultaneous detection of Eastern equine encephalitis virus (EEEV) and Western equine encephalitis virus (WEEV), we developed one duplex TaqMan real-time reverse transcriptase polymerase chain ...
Fang Lin +8 more
core +2 more sources
Heterogeneous Evolution Among SARS‐CoV‐2 Genes and Variants of Concern
Journal of Medical Virology, Volume 97, Issue 9, September 2025.ABSTRACT Challenges persist regarding the influence of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) on public health, with growing interest in future viral molecular variants. In this context, accurate predictions demand a thorough understanding of the virus's molecular evolution, especially proteins targeted by therapies, where ...
Luis Daniel González‐Vázquez +3 more
wiley +1 more source
The efficient packaging of Venezuelan equine encephalitis virus-specific RNAs into viral particles is determined by nsP1–3 synthesis [PDF]
, 2005 Alphaviruses are regarded as attractive systems for expression of heterologous genes and development of recombinant vaccines. Venezuelan equine encephalitis virus (VEE)-based vectors are particularly promising because of their specificity to lymphoid ...
Volkova, Eugenia +2 more
core +1 more source
PARP (Poly ADP‐ribose Polymerase) Family in Health and Disease
MedComm, Volume 6, Issue 9, September 2025.PARP family orchestrates ADP‐ribosylation to regulate genomic stability (DNA repair, telomeres) and metabolism (NAD⁺, glucose/lipid). Physiological roles sustain health; dysregulation drives pathologies: cancer (DNA repair addiction), neurodegeneration (parthanatos), cardiovascular disorders (hypertrophy/fibrosis), inflammation (dual role), and viral ...
Pengyuan Lei +9 more
wiley +1 more source
Alphavirus polymerase and RNA replication [PDF]
, 2017 Alphaviruses are typically arthropod-borne, and many are important pathogens such as chikungunya virus. Alphaviruses encode four nonstructural proteins (nsP1-4), initially produced as a polyprotein P1234. nsP4 is the core RNA-dependent RNA polymerase but
Ahola, Tero +2 more
core +1 more source