Results 81 to 90 of about 9,413 (173)

SARS-CoV2 Nsp3 protein triggers cell death and exacerbates amyloid β42-mediated neurodegeneration

Neural Regeneration Research
[INLINE:1] Infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) virus, responsible for the coronavirus disease 2019 (COVID-19) pandemic, induces symptoms including increased inflammatory response, severe acute respiratory ...
Aditi Singh, Anuradha Venkatakrishnan Chimata, Prajakta Deshpande, Soumya Bajpai, Anjali Sangeeth, Mrigendra Rajput, Amit Singh   +6 more
doaj   +1 more source

Severe Acute Respiratory Syndrome Coronavirus Nonstructural Proteins 3, 4, and 6 Induce Double-Membrane Vesicles

mBio, 2013
Coronaviruses (CoV), like other positive-stranded RNA viruses, redirect and rearrange host cell membranes for use as part of the viral genome replication and transcription machinery.
Megan M. Angelini, Marzieh Akhlaghpour, Benjamin W. Neuman, Michael J. Buchmeier   +3 more
doaj   +1 more source

Identification of Three Novel Linear B-Cell Epitopes in Non-Structural Protein 3 of Porcine Epidemic Diarrhea Virus Using Monoclonal Antibodies

Viruses
Porcine epidemic diarrhea virus (PEDV) is a highly pathogenic swine coronavirus that causes diarrhea and high mortality in piglets, resulting in significant economic losses within the global swine industry.
Mingjun Ye, Huixin Zhu, Zhen Yang, Yanni Gao, Juan Bai, Ping Jiang, Xing Liu, Xianwei Wang   +7 more
doaj   +1 more source

Computational approach to study the synthesis of noscapine and potential of stereoisomers against nsP3 protease of CHIKV

Heliyon, 2019
Chikungunya fever is a major public health issue in India affecting millions of people and occurs due to Chikungunya. Chikungunya virus (CHIKV) is a single stranded RNA virus from the family of Togaviridae and genus alpha virus.
Prashant Singh, Durgesh Kumar, Vijay Kumar Vishvakarma, Parul Yadav, Abhilash Jayaraj, Kamlesh Kumari   +5 more
doaj   +1 more source

READDI protocol: Crystallisation of CHIKV nsP3 macrodomain v2

The crystallization protocol and buffer conditions used to obtain reproducible Chikungunya Virus NS3 macrodomain crystals suitable for XChem fragment screening.
Jasmin Aschenbrenner, Peter Marples, michael fairhead, Andre Schutzer de Godoy, Daren Fearon   +4 more
openaire   +1 more source

Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery.

PLoS Pathogens, 2019
G3BP-1 and -2 (hereafter referred to as G3BP) are multifunctional RNA-binding proteins involved in stress granule (SG) assembly. Viruses from diverse families target G3BP for recruitment to replication or transcription complexes in order to block SG ...
Benjamin Götte, Marc D Panas, Kirsi Hellström, Lifeng Liu, Baila Samreen, Ola Larsson, Tero Ahola, Gerald M McInerney   +7 more
doaj   +1 more source

Complete genome constellations of two bovine rotavirus A strains isolated in Japan reveal a unique T9 NSP3 genotype

, 2023
Md. Amirul HASAN, Masato Suzuki, Kouji Sakai, Md Humayun Kabir, Yu MIYAOKA, Hakimullah Hakim, Chisaki KADOTA, Dany Shoham, Kazuaki Takehara   +8 more
openalex   +2 more sources

Molecular Systems Network Predicts Sars-Cov-2 NSP3 and Orf6 Role in COVID-19 Related Thrombotic Events

, 2022
Mushtaq Hussain, Fakiha Siddiqui, Syed Muhammad Omer, Anusha Amanullah, Nusrat Jabeen, Bülent Kantarcıoğlu, Jawed Fareed   +6 more
openalex   +2 more sources

In Silico studies of Natural compounds that inhibit SARS-CoV-2 Nucleocapsid Nsp1/Nsp3 proteins mediated Viral Replication and Pathogenesis [PDF]

, 2020
Hemanth Kumar Manikyam
openalex   +1 more source

Decoding chikungunya virus non-structural protein 3 interacting partners in THP-1 derived infected macrophages through proteomic profiling

Frontiers in Virology
IntroductionChikungunya virus (CHIKV), an alphavirus transmitted by mosquitoes, has instigated several epidemics in recent years, sparking intensive efforts to understand its biology.
Priyanshu Srivastava, Nimisha Mishra, Sakshi Chaudhary, Sujatha Sunil   +3 more
doaj   +1 more source