Results 121 to 130 of about 5,845 (181)

Clonación, sobre-expresión y purificación de las proteínas NSP5 y NSP6 de rotavirus en Escherichia coli [PDF]

, 2007
Tesis (Doctorado en Ciencias en Biología Molecular)"Los rotavirus representan una de las principales causas de gastroenteritis entre los niños menores de cinco años a nivel mundial.
Samaniego Hernández, Midory
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Characterization of viroplasm-like structures by co-expression of NSP5 and NSP2 across rotavirus species A to J [PDF]

Rotaviruses (RVs) are classified into nine species, A–D and F–J, with species A being the most studied. In rotavirus of species A (RVA), replication occurs in viroplasms, which are cytosolic globular inclusions composed of main building block proteins ...
Cosic, Ariana, Aguilar, Claudio, Eichwald, Catherine; https://orcid.org/, Lee, Melissa; https://orcid.org/, Tobler, Kurt; https://orcid.org/, Fraefel, Cornel; https://orcid.org/   +5 more
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The non-structural protein 5 and matrix protein are antigenic targets of T cell immunity to genotype 1 porcine reproductive and respiratory syndrome viruses

Frontiers in Immunology, 2016
The porcine reproductive and respiratory syndrome virus (PRRSV) is the cause of one of the most economically important diseases affecting swine worldwide.
Helen eMokhtar, Helen eMokhtar, Miriam ePedrera, Jean-Pierre eFrossard, Lucia eBiffar, Sabine eHammer, Lise eKvisgaard, Lars eLarsen, Graham eStewart, Satyranayrana eSomaravarapu, Falko eSteinbach, Simon Paul Graham   +11 more
doaj   +1 more source

Structural Determinants of Coronavirus Nsp5 Function and Inhibition

, 2014
Coronavirus (CoV) infections cause a number of human diseases ranging in severity from the common cold to severe acute respiratory syndrome (SARS).
Maxwell, Lindsay Alexandra
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The Role of the Host Cytoskeleton in the Formation and Dynamics of Rotavirus Viroplasms

Viruses
Rotavirus (RV) replicates within viroplasms, membraneless electron-dense globular cytosolic inclusions with liquid–liquid phase properties. In these structures occur the virus transcription, replication, and packaging of the virus genome in newly ...
Janine Vetter, Melissa Lee, Catherine Eichwald   +2 more
doaj   +1 more source

Unexpected detection of porcine rotavirus C strains carrying human origin VP6 gene

Veterinary Quarterly, 2017
Background: Rotavirus C (RVC), a known etiological agent of diarrheal outbreaks, mainly inflicts swine population globally with sporadic incidence in human, cattle, ferret, mink and dog.
Jobin Jose Kattoor, Sharad Saurabh, Yashpal Singh Malik, Shubhankar Sircar, Kuldeep Dhama, Souvik Ghosh, Krisztián Bányai, Nobumichi Kobayashi, Raj Kumar Singh   +8 more
doaj   +1 more source

The rotavirus nonstructural protein NSP5 coordinates a [2Fe-2S] iron-sulfur cluster that modulates interaction to RNA.

, 2013
International audienceDuring rotavirus infection, replication and packaging of the viral genome occur in viral factories, termed viroplasms. The viral nonstructural protein NSP5 is a major building block of viroplasms; it recruits the viral polymerase ...
Martin, Davy, d'Autreaux, Benoit, Poncet, Didier, Boussac, Alain, Poupon, Joël, Charpilienne, Annie, Parent, Aubérie   +6 more
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Emergence of a Novel G4P[6] Porcine Rotavirus with Unique Sequence Duplication in NSP5 Gene in China

Animals
Rotavirus is a major causative agent of diarrhoea in children, infants, and young animals around the world. The associated zoonotic risk necessitates the serious consideration of the complete genetic information of rotavirus.
Xia Zhou, Xueyan Hou, Guifa Xiao, Bo Liu, Handuo Jia, Jie Wei, Xiaoyun Mi, Qingyong Guo, Yurong Wei, Shao-Lun Zhai   +9 more
doaj   +1 more source

The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication

mBio
Rotavirus (RV) replication takes place in the viroplasms, cytosolic inclusions that allow the synthesis of virus genome segments and their encapsidation in the core shell, followed by the addition of the second layer of the virion.
Janine Vetter, Guido Papa, Kurt Tobler, Javier M. Rodriguez, Manuel Kley, Michael Myers, Mahesa Wiesendanger, Elisabeth M. Schraner, Daniel Luque, Oscar R. Burrone, Cornel Fraefel, Catherine Eichwald   +11 more
doaj   +1 more source

Studies On Phosphorylation And Oligomerization Of Rotavirus Nonstructural Protein 5 (NSP5) And Cellular Pathways That Regulate Virus Replication [PDF]

, 2012
Rotavirus is one of the leading etiological agents of gastroenteritis in young of many species including humans worldwide and is responsible for about 600,000 infant deaths per annum. Rotavirus belongs to the Reoviridae family, and its genome is composed
Namsa, Nima Dondu
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