Results 101 to 110 of about 283 (118)
Journal of Virological Methods, 2017 Infectious bronchitis virus (IBV) continues to be one of the most important poultry pathogens worldwide. The current commercially available enzyme-linked immunosorbent assay (ELISA) kits for IBV specific antibody detection are mostly based on the whole virion, and few serological tests based on nonstructural proteins of IBV have been developed. Herein,
Jiyong Zhou, Min Liao, Yulan Jin
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Porcine Deltacoronavirus nsp5 Antagonizes Type I Interferon Signaling by Cleaving STAT2 [PDF]
Journal of Virology, 2017 ABSTRACT Porcine deltacoronavirus (PDCoV) is an emerging swine enteropathogenic coronavirus. The first outbreak of PDCoV was announced from the United States in 2014, followed by reports in Asia. The nonstructural protein nsp5 is a 3C-like protease of coronavirus, and our previous study showed that PDCoV nsp5 inhibits type I interferon (IFN ...
Guiqing Peng +2 more
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Expression and Purification of Rotavirus Proteins NSP5 and NSP6 in Escherichia coli
Cell Biochemistry and Biophysics, 2006Rotaviruses are one of the worldwide leading causes of gastroenteritis in children under 5 yr old. The rotavirus nonstructural NSP5 is a phosphoprotein implicated in viroplasms formation, whereas NSP6 could have a possible regulatory role of NSP5. It has been reported that N- and C-termini of NSP5 are important for their function.
M, Samaniego-Hernández +4 more
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Porcine rotavirus C strains carrying human‐like NSP4 and NSP5
Zoonoses and Public Health, 2020AbstractBackgroundRotavirus C (RVC) is an enteric pathogen that affects humans and animals around the world.MethodsIn this study, we characterized the genetic diversity of RVC strains detected in asymptomatic Brazilian pigs by sequencing the NSP4, NSP5 and VP6 genes.ResultsThe results of reverse transcription polymerase chain reaction showed that 53 of
Fábio Burack Costa +4 more
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Porcine deltacoronavirus nsp5 inhibits interferon-β production through the cleavage of NEMO
Virology, 2017 Porcine deltacoronavirus (PDCoV) causes acute enteric disease and mortality in seronegative neonatal piglets. Previously we have demonstrated that PDCoV infection suppresses the production of interferon-beta (IFN-β), while the detailed mechanisms are poorly understood.
Mohamed Frahat Foda +2 more
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The Role of nsp5 in SARS-CoV-2
Theoretical and Natural ScienceSARS-CoV-2, the causative agent of the COVID-19 pandemic, is a single-stranded positive-sense RNA virus belonging to the coronavirus family. It emerged at the end of 2019 and has swiftly disseminated globally, presenting an unparalleled threat to public health worldwide.
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