Results 81 to 90 of about 7,665 (202)
Zoonoses and Public Health, Volume 73, Issue 1, Page 95-106, February 2026.ABSTRACT Introduction Black flies (Simuliidae) are globally distributed blood‐feeding arthropods and vectors of viral, bacterial, and parasitic pathogens to many animal species, including humans. We investigated the occurrence of selected vector‐borne pathogens in black flies in South Moravia, Czech Republic, and evaluated their possible role in the ...
Silvie Šikutová +10 more
wiley +1 more source
Effects of intrabodies specific for rotavirus NSP5 during the virus replicative cycle
Journal of General Virology, 2004 Intracellular antibodies or intrabodies (ICAbs) have great potential in protein knockout strategies for intracellular antigens. In this study, they have been used to investigate the role of the rotavirus non-structural protein NSP5 in the virus replication cycle. Intracellular antibody-capture technology was used to select single-chain Fv format (scFv)
VASCOTTO F +4 more
openaire +3 more sources
Food Frontiers, Volume 7, Issue 1, January 2026.The choline‐binding protein A (CbpA) was shown to mediate adhesion of probiotic Ligilactobacillus salivarius strains to human intestinal epithelial cells (IECs). A knockout mutant lacking the CbpA protein derived from the immunomodulatory porcine strain L. salivarius FFIG58 was obtained. The CbpA is a key surface protein of L.
Yoshiya Imamura +13 more
wiley +1 more source
Rotavirus NSP5 phosphorylation is up-regulated by interaction with NSP2.
Journal of General Virology, 1998 We have previously shown that a number of isoforms of the non-structural rotavirus protein NSP5 are found in virus-infected cells. These isoforms differ in their level of phosphorylation which, at least in part, appears to occur through autophosphorylation. NSP5 co-localizes with another non-structural protein, NSP2, in the viroplasms of infected cells
I, Afrikanova +3 more
openaire +2 more sources
SNRK3.15 Is a Crucial Component of the Sulfur Deprivation Response in Arabidopsis thaliana
Plant Direct, Volume 10, Issue 1, January 2026.ABSTRACT Sulfate deprivation (–S) results in numerous metabolic and phenotypic alterations in plants. Kinases are often key players in transducing nutrient status signals to molecular components involved in metabolic and developmental program regulation, but despite the physiological importance of sulfur, to date, no signaling kinases have been ...
Anastasia Apodiakou +8 more
wiley +1 more source
The Journal of biological chemistry, 2015 All coronaviruses, including the recently emerged Middle East respiratory syndrome coronavirus (MERS-CoV) from the β-CoV subgroup, require the proteolytic activity of the nsp5 protease (also known as 3C-like protease, 3CL(pro)) during virus replication, making it a high value target for the development of anti-coronavirus therapeutics.
Tomar, Sakshi +8 more
openaire +2 more sources
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Porcine reproductive and respiratory syndrome virus (PRRSV) continues to cause substantial economic losses worldwide, and certain lineages circulate in specific countries. Lineage Korean A (LKA), B (LKB), and C (LKC) have been reported exclusively in Korea. However, studies on LKA and LKB have been limited to strains isolated before 2015. In this study,
Hyejin Na, Chanhee Chae, Nan-hua Chen
wiley +1 more source
Natural Products as Potential Resource Library for Control of Major Swine Enteric Viruses
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Major swine enteric viruses (SEVs), including porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), swine acute diarrhea syndrome coronavirus (SADS‐CoV), and porcine rotavirus (PoRV), cause severe gastrointestinal diseases in pigs, leading to huge economic losses to the swine industry ...
Jialu Zhang +7 more
wiley +1 more source
Journal of Medical Virology, Volume 97, Issue 12, December 2025.ABSTRACT HCoV‐OC43 genomes and their evolution are scarcely studied worldwide and in France, with only 361 genomes available as of October 2023. Here, an in‐house PCR amplification system was implemented to obtain retrospectively by next‐generation sequencing, then analyze HCoV‐OC43 genomes for infections diagnosed with this virus in southern France ...
Hikmat Houmadi +10 more
wiley +1 more source
APMIS, Volume 133, Issue 12, December 2025.ABSTRACT RNA hairpins may constitute a foundation of genetic evolution both in viruses and other organisms. Stem‐loops theoretically comprise a stable part, the double‐stranded stem, and a single‐stranded loop allowing evolution. Here we tested for SARS‐CoV‐2 if “fertile” mutations were in loops while mutations in stems were poorly tolerated and rarely
Philippe Colson +5 more
wiley +1 more source