Results 141 to 150 of about 908,554 (203)

NTRK amplification occurs frequently in pan-TRK immunopositive dedifferentiated liposarcomas

Pathology and Oncology Research
The neurotrophic tyrosine kinase receptor (NTRK) gene family is of rising importance as their fusions are oncogenic, and specific target drugs are available to inhibit the chimera proteins.
Zoltán Lippai, Gergő Papp, Károly Szuhai, Johanna Sápi, Katalin Dezső, Zoltán Sápi   +5 more
doaj   +1 more source

Improved guidance is needed to optimise diagnostics and treatment of patients with thyroid cancer in Europe [PDF]

Although thyroid cancer (TC) is generally associated with a favourable prognosis, there are certain high-risk groups with a clear unmet therapeutic need.
Alvarez, Clara V., Camacho, Pilar, de la Fouchardière, Christelle, Fugazzola, Laura, Jarząb, Barbara, Locati, Laura D., Netea-Maier, Romana, Peeters, Robin P., Simon, Iris M.   +8 more
core   +3 more sources

Molecular and cytogenetic features of NTRK fusions enriched in BRAF and RET double-negative papillary thyroid cancer.

Journal of Molecular Diagnostics, 2023
Shafei Wu, Yuanyuan Liu, Kaimi Li, Zhiyong Liang, Xuan Zeng   +4 more
semanticscholar   +1 more source

NTRK1-rearranged histiocytosis:clinicopathologic and molecular features [PDF]

Non-Langerhans cell histiocytoses are a diverse group of histiocytic diseases. Different entities are defined based on clinical, histopathologic, and/or molecular characteristics. This study aimed to define NTRK-rearranged histiocytosis.
Babor, Florian, Bartlett, Allison L., Bhattacharya, Arunaloke, Bonsang, Benjamin, Borkhardt, Arndt, Carlsen, Eric D., de Vries, Andrica C.H., Dhar, Subhra, Diamond, Eli L., Donadieu, Jean, Drabent, Philippe, Durham, Benjamin H., Emile, Jean François, Fragneau, Rivers, Fraitag, Sylvie, Haroche, Julien, Ho, Jonhan, Hélias-Rodzewicz, Zofia, Héritier, Sébastien, Jankofsky, Martin, Jullié, Marie Laure, Karunamurthy, Arivarasan D., Kemps, Paul G., Krsková, Lenka, Kumar, Ashish R., Leguit, Roos J., Lorsbach, Robert, Picarsic, Jennifer L., Roy, Somak, Santi, Mariarita, Svojgr, Karel, van Halteren, Astrid G.S., van Laar, Jan A.M., Verdijk, Robert M., Zlocha, Jozef   +34 more
core   +1 more source

Challenges in the Diagnosis of NTRK Fusion-Positive Cancers [PDF]

Journal of Thoracic Oncology, 2020
Oliver, Gautschi, Lukas, Bubendorf, Serge, Leyvraz, Roopika, Menon, Joachim, Diebold   +4 more
openaire   +2 more sources

NTRK Fusions Can Co-Occur With H3K27M Mutations and May Define Druggable Subclones Within Diffuse Midline Gliomas. [PDF]

J Neuropathol Exp Neurol, 2021
Dahl NA, Donson AM, Sanford B, Wang D, Walker FM, Gilani A, Foreman NK, Tinkle CL, Baker SJ, Hoffman LM, Venkataraman S, Vibhakar R.   +11 more
europepmc   +1 more source

A Case Report of Lung Adenocarcinoma with EGFR G719A Mutation 
and LMNA-NTRK1 Fusion

Chinese Journal of Lung Cancer
Fusion variations of neurotrophic receptor tyrosine kinase (NTRK) are oncogenic drivers in various solid tumors such as breast cancer, salivary gland carcinoma, infant fibrosarcoma, etc.
Shiqi SONG, Yaxian YANG, Weiquan LUO, Yueya LIANG, Qi LI, Tongxu ZHUO, Weibin XIONG, Jian HUANG   +7 more
doaj   +1 more source

I.18-1 NTRK Fusion Proteins [PDF]

Journal of Thoracic Oncology, 2019
openaire   +1 more source

71P NTRK gene fusions in bilio-pancreatic cancers [PDF]

Annals of Oncology, 2020
A. Demols, L. Perez-Casanova, L. Rocq, M. Charry, N. De Nève, A. Verrellen, A. Ramadhan, C. Van Campenhout, S. De Clercq, C. Maris, J. Closset, V. Lucidi, I. Salmon, N. D'Haene   +13 more
openaire   +1 more source

A phase II trial of larotrectinib in tumors with NTRK fusions or extremes of NTRK mRNA overexpression identified by comprehensive genomic profiling. [PDF]

Oncologist
Thavaneswaran S, Sim HW, Grady J, Espinoza D, Huang ML, Lin F, McGrath M, Desai J, Charakidis M, Brown M, Kansara M, Simes J, Thomas D.   +12 more
europepmc   +1 more source