Results 71 to 80 of about 31,285 (260)

Infection-induced chromatin modifications facilitate translocation of herpes simplex virus capsids to the inner nuclear membrane.

open access: yesPLoS Pathogens, 2021
Herpes simplex virus capsids are assembled and packaged in the nucleus and move by diffusion through the nucleoplasm to the nuclear envelope for egress.
Vesa Aho   +7 more
doaj   +1 more source

Tegument Protein pp150 Sequence-Specific Peptide Blocks Cytomegalovirus Infection

open access: yesViruses, 2021
Human cytomegalovirus (HCMV) tegument protein pp150 is essential for the completion of the final steps in virion maturation. Earlier studies indicated that three pp150nt (N-terminal one-third of pp150) conformers cluster on each triplex (Tri1, Tri2A and ...
Dipanwita Mitra   +4 more
doaj   +1 more source

A Far-Ultraviolet Survey of 47 Tucanae.II The Long-Period Cataclysmic Variable AKO 9

open access: yes, 2003
We present time-resolved, far-ultraviolet (FUV) spectroscopy and photometry of the 1.1 day eclipsing binary system AKO 9 in the globular cluster 47 Tucanae. The FUV spectrum of AKO 9 is blue and exhibits prominent C IV and He II emission lines.
Auriere M.   +19 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

KOI-3278: A Self-Lensing Binary Star System

open access: yes, 2014
Over 40% of Sun-like stars are bound in binary or multistar systems. Stellar remnants in edge-on binary systems can gravitationally magnify their companions, as predicted 40 years ago.
Agol, Eric, Kruse, Ethan
core   +1 more source

Toxoplasma gondii Syntaxin 6 is required for vesicular transport between endosomal-like compartments and the Golgi Complex [PDF]

open access: yes, 2013
Apicomplexans are obligate intracellular parasites that invade the host cell in an active process that relies on unique secretory organelles (micronemes, rhoptries and dense granules) localized at the apical tip of these highly polarized eukaryotes ...
Clucas, Caroline   +4 more
core   +1 more source

Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1

open access: yesScientific Reports, 2018
TDP-43 and FUS are nuclear proteins with multiple functions in mRNA processing. They play key roles in ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia), where they are partially lost from the nucleus and aggregate in the cytoplasm of
Helena Ederle   +7 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Background subtraction and transient timing with Bayesian Blocks

open access: yes, 2015
Aims: To incorporate background subtraction into the Bayesian Blocks algorithm so that transient events can be timed accurately and precisely even in the presence of a substantial, rapidly variable, background. Methods: We developed several modifications
Schwope, Axel D., Worpel, Hauke
core   +1 more source

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