Results 61 to 70 of about 1,784 (124)
Soil Organic Matter Stabilization by Polyvalent Cations in a Buried Alkaline Soil
Abstract Buried paleosols can store large quantities of organic carbon (C), much of which persists for millennia due to isolation from surface processes that promote decomposition. Subsoil organic matter (SOM) persistence is often enhanced by mineral associations and ionic conditions—particularly high clay content and polyvalent cations—that limit ...
Manisha Dolui +11 more
wiley +1 more source
Herpesviruses and Intermediate Filaments: Close Encounters with the Third Type [PDF]
Intermediate filaments (IF) are essential to maintain cellular and nuclear integrity and shape, to manage organelle distribution and motility, to control the trafficking and pH of intracellular vesicles, to prevent stress-induced cell death, and to ...
Hertel, Laura
core +3 more sources
Plasma Proteome Profiling of Centenarian Across Switzerland Reveals Key Youth‐Associated Proteins
We characterized the plasma proteomic profiles of centenarians from the SWISS100 cohort, identifying 583 differentially expressed proteins compared to younger and geriatric groups. Cross‐validation with the independent datasets NECS and the TAME consortium confirmed a robust aging signature, while fractional polynomial regressions revealed a specific ...
Flavien Delhaes +8 more
wiley +1 more source
Molecular Studies on Plasmodium During Development in the Mosquito
Among the factors that regulate transmission of malaria are host-derived immune factors which can inhibit the progression of Plasmodium through the mosquito. This thesis addresses whether members of a family of LCCL/lectin Adhesive–like Proteins (LAPs)
Armson, Rebecca, Armson, Rebecca
core +1 more source
Beyond Conventional Cooling: Advanced Micro/Nanostructures for Managing Extreme Heat Flux
This review examines the design, application, and manufacturing of biomimetic or engineered micro/nanostructures for managing high heat‐flux in multi‐level electronics by enhancing conductive, convective, phase‐changing, and radiative heat transfer mechanisms, highlighting their potential for efficient, targeted thermal management, and future prospects.
Yuankun Zhang +7 more
wiley +1 more source
Summary diagram for the role of CypA in chemoresistance in non‐small cell lung cancer (NSCLC). CypA is overexpressed in chemoresistance NSCLC and drives therapeutic evasion by competitively binding to the K37 site of SLC7A11, thereby blocking TRIM3 mediated K11‐linked ubiquitination and proteasomal degradation, ultimately inhibiting lipid peroxidation ...
Zhongcheng Wang +9 more
wiley +1 more source
Glutathione (GSH) defines oxidative balance, but can it directly tune central metabolism? The research reveals that GSH binds and potently activates pyruvate kniase M2 (PKM2), rewiring glycolysis and dictating ferroptosis sensitivity. Combining GSH depletion with PKM2 activation triggers mitochondrial damage and lipid peroxidation, profoundly ...
Tsan‐Jan Chen +17 more
wiley +1 more source
An anion‐π+ type AIE photosensitizer (TMTPA NPs) with NIR emission was successfully developed through a sulfidation strategy. With its exceptional mitochondrial targeting abilities and efficient Type I ROS generation, TMTPA NPs effectively trigger ferroptosis.
Lingxiu Liu +6 more
wiley +1 more source
Abstract Climate and land‐use change are dramatically altering the frequency, intensity, and extent of ecological disturbances, which threaten the persistence of at‐risk species. To curb the pace and scale of disturbances, balance management and conservation priorities, and alleviate associated population declines, managers require high‐quality ...
Jason M. Winiarski +13 more
wiley +1 more source
Progress in the detection of gut microbiota based on microfluidic technology
Abstract Gut microbiota, a complex microbial community in the human intestine, are vital for digestion, nutrient absorption, and immune regulation, maintaining gut micro‐ecological balance. Accurate detection of its composition, structure, and function is crucial for understanding the relationship between health and disease, early disease diagnosis ...
Yuan Tan +3 more
wiley +1 more source

