Results 71 to 80 of about 2,002,555 (370)
Immunocytochemistry of nuclear domains and Emery-Dreifuss muscular dystrophy pathophysiology
European Journal of Histochemistry, 2009 The present review summarizes recent cytochemical findings on the functional organization of the nuclear domains, with a particular emphasis on the relation between nuclear envelope- associated proteins and chromatin.
NM Maraldi +8 more
doaj +1 more source
The SUN protein Mps3 is required for spindle pole body insertion into the nuclear membrane and nuclear envelope homeostasis. [PDF]
PLoS Genetics, 2011 The budding yeast spindle pole body (SPB) is anchored in the nuclear envelope so that it can simultaneously nucleate both nuclear and cytoplasmic microtubules. During SPB duplication, the newly formed SPB is inserted into the nuclear membrane.
Jennifer M Friederichs +9 more
doaj +1 more source
The Biology of the Nuclear Envelope and Its Implications in Cancer Biology
International Journal of Molecular Sciences, 2019 The formation of the nuclear envelope and the subsequent compartmentalization of the genome is a defining feature of eukaryotes. Traditionally, the nuclear envelope was purely viewed as a physical barrier to preserve genetic material in eukaryotic cells.
M. Alvarado-Kristensson, C. A. Rosselló
semanticscholar +1 more source
Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations [PDF]
, 2005 Gene-poor human chromosomes are reproducibly found at the nuclear periphery in proliferating cells. There are a number of inner nuclear envelope proteins that may have roles in chromosome location and anchorage, e.g. emerin and A-type lamins.
Bridger, JM +3 more
core +1 more source
STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap
Nature Communications, 2018 The perinuclear actin cap is an important cytoskeletal structure that regulates nuclear morphology and re-orientation during front-rear polarisation. The mechanisms regulating the actin cap are currently poorly understood.
Anna Woroniuk +12 more
semanticscholar +1 more source
Viruses, 2019 During lytic herpes simplex virus 1 (HSV-1) infection, the expansion of the viral replication compartments leads to an enrichment of the host chromatin in the peripheral nucleoplasm.
Vesa Aho +10 more
doaj +1 more source
PLoS Pathogens, 2021 Herpes simplex virus capsids are assembled and packaged in the nucleus and move by diffusion through the nucleoplasm to the nuclear envelope for egress.
Vesa Aho +7 more
doaj +1 more source
Fantastic nuclear envelope herniations and where to find them.
Biochemical Society Transactions, 2018 Morphological abnormalities of the bounding membranes of the nucleus have long been associated with human diseases from cancer to premature aging to neurodegeneration.
David J. Thaller, C. Patrick Lusk
semanticscholar +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Ultradonut Topology of the Nuclear Envelope [PDF]
Biophysical Journal, 2016 Significance Lipid membranes exhibit a variety of morphologies tailored to perform specific functions of cells and their organelles. A unique lipid structure is the nuclear envelope which houses the genome and plays a vital role in genome organization and signaling pathways.
University of Houston, Houston, TX, USA ( host institution ) +3 more
openaire +5 more sources