Results 51 to 60 of about 688,071 (260)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Evidence of a thermo-diffusion pinch on particle transport in FTU discharges close to density limit
Nuclear Materials and Energy, 2017 In FTU, the density profile in the presence of large MARFE becomes more and more peaked with increasing density, forming strong density gradients close to the radial region affected by the MARFE.
O. Tudisco +7 more
doaj +1 more source
Overview of the ITER TBM program
He jishu, 2022 The tritium breeding blanket (TBB) technology is one of the key technologies to be solved and also one of three major issues in the development of fusion reactor in the future. The international thermonuclear experimental reactor (ITER) will be the first
SHENG Qian +6 more
doaj +1 more source
Microscopic study of $^{40}$Ca+$^{58,64}$Ni fusion reactions
, 2016 Background: Heavy-ion fusion reactions at energies near the Coulomb barrier are influenced by couplings between the relative motion and nuclear intrinsic degrees of freedom of the colliding nuclei.
Bourgin, D. +3 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
PlasmaThe mechanisms by which rotation influences zonal flows (ZFs) in plasma are incompletely understood, presenting a significant challenge in the study of plasma dynamics.
Xinliang Xu +8 more
doaj +1 more source
Fusion of radioactive $^{132}$Sn with $^{64}$Ni
, 2007 Evaporation residue and fission cross sections of radioactive $^{132}$Sn on $^{64}$Ni were measured near the Coulomb barrier. A large sub-barrier fusion enhancement was observed.
A. Galindo-Uribarri +21 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source