Results 201 to 210 of about 270,346 (298)

PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2. [PDF]

Mol Ther
Yang CL, Wang FX, Luo JH, Rong SJ, Lu WY, Chen QJ, Xiao J, Wang T, Song DN, Liu J, Mo Q, Li S, Chen Y, Wang YN, Liu YJ, Yan T, Gu WK, Zhang S, Xiong F, Yu QL, Zhang ZY, Yang P, Liu SW, Eizirik D, Dong LL, Sun F, Wang CY.   +26 more
europepmc   +1 more source

Preparation, Component Identification, and Antioxidant Activity of Anthocyanins From Punica granatum “Tunisia”

AgriFood: Journal of Agricultural Products for Food, EarlyView.
The preparation for Tunisian pomegranate anthocyanin extract. The molecular mechanisms underlying the antioxidant effects of these compounds were investigated using network pharmacology and molecular docking. Antioxidant activity was evaluated through DPPH, ABTS, and FRAP assays, whereas the effects on oxidative stress and inflammation were examined in
Jing Zhang, Xu‐han Yang, Meng‐qi Zhang, Xu Guo, Ning‐yang Li, Fang‐yu Long, Chao Liu   +6 more
wiley   +1 more source

Nemo-like kinase disrupts nuclear import and drives TDP43 mislocalization in ALS. [PDF]

J Clin Invest
Bekier ME, Pinarbasi E, Krishnan G, Mesojedec JJ, Hurley M, Harikumar Sheela H, Collins CA, Ghaffari L, de Majo M, Ullian EM, Koontz M, Coleman S, Li X, Tank EM, Waksmacki J, Gao FB, Barmada SJ.   +16 more
europepmc   +1 more source

Computer Vision Pipeline for Image Analysis for Freeze‐Fracture Electron Microscopy: Rosette Cellulose Synthase Complexes Case

Advanced Intelligent Discovery, EarlyView.
This paper presents a computer vision (deep learning) pipeline integrating YOLOv8 and YOLOv9 for automated detection, segmentation, and analysis of rosette cellulose synthase complexes in freeze‐fracture electron microscopy images. The study explores curated dataset expansion for model improvement and highlights pipeline accuracy, speed ...
Siri Mudunuri, Leala Carbonneau, Eric M. Roberts, Alison W. Roberts, Candace H. Haigler, Alexey V. Gulyuk, Yaroslava G. Yingling   +6 more
wiley   +1 more source

POM121 O-GlcNAcylation facilitates bone metastasis in non-small cell lung cancer through enhanced c-MYC nuclear import and ECM reprogramming. [PDF]

Oncogene
Ren YZ, Zhao MN, Du FL, Wu L, Wang L, Lou JT.   +5 more
europepmc   +1 more source

MusicSwarm: Biologically Inspired Intelligence for Music Composition

Advanced Intelligent Systems, EarlyView.
Biologically inspired swarms of frozen foundation models self‐organize to compose complex music without fine‐tuning. By coordinating through stigmergic signals, decentralized agents dynamically evolve specialized roles and adapt to solve complex tasks.
Markus J. Buehler
wiley   +1 more source

HBV p22-interacting protein C1QBP inhibits viral replication through impeding nucleocapsid formation and nuclear import. [PDF]

PLoS Pathog
Peng X, Liu CD, Mitra B, Kim ES, Sun N, Jurado A, Zhang H, Li S, Zhou T, Guo H.   +9 more
europepmc   +1 more source

Owning Home, Finding Belonging: Relational Meanings of Homeownership for Migrant Healthcare Workers in Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT Migrant healthcare workers in Australia find themselves at the centre of three intersecting concerns, often presented as ‘crises’ in contemporary discourse: the ‘care crisis’, the ‘housing crisis’ and the ‘migration crisis.’ Yet their own perspectives on these issues are rarely foregrounded. This paper explores the role of homeownership in the
Leah Williams Veazey
wiley   +1 more source

DEAD-box helicase gcDDX56 disrupts IRF3 nuclear import complex and promotes nuclear IRF3 degradation for enhancing GCRV replication. [PDF]

J Virol
Xiao LL, Chen Y, Zhang J, Xiao J, Feng H, Chang MX.   +5 more
europepmc   +1 more source

Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding, Yingjie Zhang, Li Zhang, Xinou Zheng, Miaomiao Niu, Yunxiao Jia, Xuezhuang Li, Hua Chen, Chao Guo, Tao Jiang, Yuqiong Zhao   +10 more
wiley   +1 more source