Results 81 to 90 of about 75,707 (295)
Nature Methods, 2007 Crystal structures of a transporter with different substrates lead to the design of a pathway-specific nuclear import inhibitor.
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Multimodal Data‐Driven Microstructure Characterization
Advanced Engineering Materials, EarlyView.A self‐consistent autonomous workflow for EBSP‐based microstructure segmentation by integrating PCA, GMM clustering, and cNMF with information‐theoretic parameter selection, requiring no user input. An optimal ROI size related to characteristic grain size is identified.
Qi Zhang +4 more
wiley +1 more source
HIV-1 resists MxB inhibition of viral Rev protein
Emerging Microbes and Infections, 2020 The interferon-inducible myxovirus resistance B (MxB) protein has been reported to inhibit HIV-1 and herpesviruses by blocking the nuclear import of viral DNA.
Zhen Wang +10 more
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Advanced Engineering Materials, EarlyView.Knowledge‐based atomistic workflows are presented for mechanical and thermodynamic properties. By coupling modular simulations with ontology‐aligned metadata and provenance, Fe case studies on elastic behavior, defects, thermal properties, and Hall–Petch strengthening reveal how FAIR, queryable, and reusable simulation data can be generated. Mechanical
Abril Azócar Guzmán +5 more
wiley +1 more source
Influence of Geometric Design on Mechanical Performance of Auxetic Metastructure
Advanced Engineering Materials, EarlyView.Strategic geometric reinforcement transforms auxetic performance. This study evaluates 3D‐printed arrowhead metastructures, revealing that a modified design with local ring reinforcement suppresses premature failure to achieve superior energy absorption and structural efficiency.
Muhammad Gulzari +3 more
wiley +1 more source
Frontiers in Plant Science, 2018 Proteins of the Poly(ADP-Ribose) Polymerase (PARP) family modify target proteins by covalent attachment of ADP-ribose moieties onto amino acid side chains.
Chao Chen +3 more
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The SMN protein is a key regulator of nuclear architecture in differentiating neuroblastoma cells
, 2009 The cell nucleus contains two closely related structures, Cajal bodies (CBs) and gems. CBs are the first site of accumulation of newly assembled splicing snRNPs (small nuclear ribonucleoproteins) following their import into the nucleus, before they form ...
Nicholas P. Kinnear +9 more
core +1 more source
The Journal of Cell Biology, 2006 ![Graphic][1] Import time (red) decreases and efficiency (blue) increases with more importin β. Faster, better import is gained by increasing levels of the importin β nuclear transport receptor, according to Yang and Musser (page [951][2]).
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Advanced Functional Materials, EarlyView.A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo +7 more
wiley +1 more source
Regulated Transport into the Nucleus of Herpesviridae DNA Replication Core Proteins
Viruses, 2013 The Herpesvirdae family comprises several major human pathogens belonging to three distinct subfamilies. Their double stranded DNA genome is replicated in the nuclei of infected cells by a number of host and viral products.
Alessandro Ripalti +6 more
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