Results 101 to 110 of about 163,417 (257)
Summary: Tcrb locus V(D)J recombination is regulated by positioning at the nuclear periphery. Here, we used DamID to profile Tcrb locus interactions with the nuclear lamina at high resolution.
Shiwei Chen+7 more
doaj
Extreme wrinkling of the nuclear lamina is a morphological marker of cancer
Nuclear atypia is a hallmark of cancer. A recent model posits that excess surface area, visible as folds/wrinkles in the lamina of a rounded nucleus, allows the nucleus to take on diverse shapes with little mechanical resistance.
Ting-Ching Wang+10 more
doaj +1 more source
This work demonstrates an interphase strain engineering strategy to regulate capacitive energy storage performance in high‐entropy oxide thin films. Through introducing pyrochlore nanocolumns, the polarization response of perovskite unit cells is strengthened, yielding recoverable energy densities up to 93 J cm−3 with an efficiency of 83% under ...
Hao Luo+11 more
wiley +1 more source
The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence [PDF]
AKTIP is a shelterin-interacting protein required for replication of telomeric DNA. Here, we show that AKTIP biochemically interacts with A- and B-type lamins and affects lamin A, but not lamin C or B, expression.
Astrologo, Letizia+14 more
core +2 more sources
Quadratic forms of rank 1, closed zones and laminae [PDF]
For a given lattice, we establish an equivalence involving a closed zone of the corresponding Voronoi polytope, a lamina hyperplane of the corresponding Delaunay partition and a quadratic form of rank 1 being an extreme ray of the corresponding L-type domain.
arxiv
In this work, it is developed a multifunctional polyfluoride ionogel via in situ thermal polymerization to encapsulate lithium metal anodes, integrating flame‐retardant capability, hydrophobicity, dynamic self‐healing behavior, and high ionic conductivity.
Ting Li+10 more
wiley +1 more source
Molecular Image Analysis: Quantitative Description and Classification of the Nuclear Lamina in Human Mesenchymal Stem Cells [PDF]
The nuclear lamina is an intermediate filament network that provides a structural framework for the cell nucleus. Changes in lamina structure are found during changes in cell fate such as cell division or cell death and are associated with human diseases.
Dirks, Roeland W.+5 more
core +3 more sources
Lamin A/C Mechanotransduction in Laminopathies
Mechanotransduction translates forces into biological responses and regulates cell functionalities. It is implicated in several diseases, including laminopathies which are pathologies associated with mutations in lamins and lamin-associated proteins ...
Francesca Donnaloja+3 more
doaj +1 more source
Mass in the Hyperbolic Plane [PDF]
The notions of mass and center of mass are extended to laminae of the hyperbolic plane. The resulting formulae contain many surprises.
arxiv
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source