Results 271 to 280 of about 1,676,612 (335)

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

Advanced Science, EarlyView.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian, Chenghong Hu, Yong Xu, Wentao Xu, Zhe Wang, Wan Gan, Weiyang Tang, Lijiang Huang, Aleksandr V. Samorodov, Yi Wang   +9 more
wiley   +1 more source

Faculty Opinions recommendation of Nuclear lamina integrity is required for proper spatial organization of chromatin in Drosophila.

, 2019
Tamar Schlick, Stephanie Portillo‐Ledesma   +1 more
openalex   +2 more sources

Spatial chromatin organization and gene regulation at the nuclear lamina.

Current Opinion in Genetics and Development, 2019
Isabel Guerreiro, Jop Kind
semanticscholar   +1 more source

Faculty Opinions recommendation of Mechanosensing by the Lamina Protects against Nuclear Rupture, DNA Damage, and Cell-Cycle Arrest.

, 2019
Michael F. Olson
openalex   +2 more sources

Spontaneous Strain‐Spin Transition Coupling Molecular Crystal with Thermal Magnetic Memory Effect, Anisotropic High‐κ and Switchable Dielectric Permittivity

Advanced Science, EarlyView.
A radical salt undergoes a paraelastic‐ferroelastic phase transition, which is coupled with spin‐Peierls transition, resulting in it integrating self‐strain, spin bistability, switchable dielectric and high‐ properties. Abstract Materials that exhibit controllable changes in electrical, magnetic, or spontaneous strain properties, particularly those ...
Xuan‐Rong Chen, Zhang‐Ni He, Yin Qian, Wei Wei, Zheng‐Fang Tian, Xiao‐Ming Ren   +5 more
wiley   +1 more source

Somatotopy in the medullary dorsal horn as a basis for orofacial reflex behavior [PDF]

, 2017
Gan, Qi, Pan, BingBing, Panneton, W. Michael   +2 more
core   +2 more sources

Emerin preserves stem cell survival through maintenance of centrosome and nuclear lamina structure.

Development
Jones SD, Miller JEB, Amos MM, Hernández JM, Piaszynski KM, Geyer PK.   +5 more
europepmc   +1 more source

Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction

Cell, 2017
A. Poleshko, P. Shah, Mudit Gupta, A. Babu, M. Morley, Lauren J. Manderfield, Jamie L. Ifkovits, D. Calderon, H. Aghajanian, Javier E. Sierra-Pagán, Zheng Sun, Qiaohong Wang, Li Li, N. Dubois, E. Morrisey, M. Lazar, Cheryl L Smith, Jonathan A. Epstein, Rajan Jain   +18 more
semanticscholar   +1 more source

A Novel OsMPK6‐OsMADS47‐PPKL1/3 Module Controls Grain Shape and Yield in Rice

Advanced Science, EarlyView.
OsMADS47 is identified as a key regulator governing rice grain morphology. Phosphorylation‐dependent regulation of its activity directs the development of slender versus round grains, modulating both yield and appearance. This mechanism bridges cellular signaling with transcriptional regulation, establishing a molecular framework for grain optimization.
Jingjing Fang, Yan Chun, Fan Zhang, Tingting Guo, Mengmeng Ren, Jinfeng Zhao, Shoujiang Yuan, Wensheng Wang, Yunhai Li, Xueyong Li   +9 more
wiley   +1 more source

Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy

Advanced Science, EarlyView.
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao, Xianping Liu, Xu Chu, Feixiang Chen, Ruicheng Shi, Zonghao Liu, Yelin Wu, Yanyan Liu, Wenbo Bu   +8 more
wiley   +1 more source