A constitutive region is responsible for nuclear targeting of 4.1R: modulation by alternative sequences results in differential intracellular localization [PDF]
, 2000 Carlos M. Luque, Isabel Correas
openalex +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
On the Nuclearity of Dual Groups [PDF]
arXiv, 2012 We prove that the dual space of a locally convex nuclear $k_\omega$ vector space endowed with the compact--open topology is a locally convex nuclear vector space. An analogous result is shown for nuclear groups. As a consequence of this, we obtain that nuclear $k_\omega$--groups are strongly reflexive.
arxiv
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Low Effectiveness of the Introduction of pmaxGFP into Primary Human Coronary Endothelial Cells Using Cell-Penetrating Peptides and Nuclear-Localization Sequences in Non-Covalent Interactions [PDF]
, 2021 Wioletta Zielińska +4 more
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CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Molecular Oncology, EarlyView.Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki +2 more
wiley +1 more source
1334. Addition of Nuclear Localization Signal Sequences from Both the HIV-1 Matrix and the HIV-1 Vpr Proteins into a Non-Viral Gene Delivery System Produces Equally Efficient Transfection in Dividing and Growth-Arrested HeLa Cells [PDF]
, 2002 openalex +1 more source
Sequence Determinants of Human Junctophilin-2 Protein Nuclear Localization and Phase Separation [PDF]
, 2021 Ang Guo, Wenjuan Fang, Savannah Gibson
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Decoupling Dipolar Interactions in Dense Spin Ensembles [PDF]
arXivDense spin ensembles in solids present a natural platform for studying quantum many-body dynamics. Multiple-pulse coherent control can be used to manipulate the magnetic dipolar interaction between the spins to engineer their dynamics. Here, we investigate the performance of a series of well-known pulse sequences that aim to suppress inter-spin dipolar
arxiv
Central sequence C*-algebras and tensorial absorption of the Jiang-Su algebra [PDF]
arXiv, 2012 We study properties of the central sequence algebra of a C*-algebra, and we present an alternative approach to a recent result of Matui and Sato. They prove that every unital separable simple nuclear C*-algebra, whose trace simplex is finite dimensional, tensorially absorbs the Jiang-Su algebra if and only if it has the strict comparison property.
arxiv