Results 71 to 80 of about 932,695 (350)

CTNNBL1 Is a Novel Nuclear Localization Sequence-binding Protein That Recognizes RNA-splicing Factors CDC5L and Prp31

open access: yesJournal of Biological Chemistry, 2011
Nuclear proteins typically contain short stretches of basic amino acids (nuclear localization sequences; NLSs) that bind karyopherin α family members, directing nuclear import.
K. Ganesh   +5 more
semanticscholar   +1 more source

Identification of a classical bipartite nuclear localization signal in the Drosophila TEA/ATTS protein scalloped. [PDF]

open access: yesPLoS ONE, 2011
Drosophila melanogaster wing development has been shown to rely on the activity of a complex of two proteins, Scalloped (Sd) and Vestigial (Vg). Within this complex, Sd is known to provide DNA binding though its TEA/ATTS domain, while Vg modulates this ...
Adam C Magico, John B Bell
doaj   +1 more source

Multiple-pulse coherence enhancement of solid state spin qubits [PDF]

open access: yesPhys. Rev. Lett. 98, 077601 (2007), 2006
We describe how the spin coherence time of a localized electron spin in solids, i.e. a solid state spin qubit, can be prolonged by applying designed electron spin resonance pulse sequences. In particular, the spin echo decay due to the spectral diffusion of the electron spin resonance frequency induced by the non-Markovian temporal fluctuations of the ...
arxiv   +1 more source

Tightness and weak convergence in the topology of local uniform convergence for stochastic processes in the dual of a nuclear space [PDF]

open access: yesarXiv, 2023
Let $\Phi'$ denote the strong dual of a nuclear space $\Phi$ and let $C_{\infty}(\Phi')$ be the collection of all continuous mappings $x:[0,\infty) \rightarrow \Phi'$ equipped with the topology of local uniform convergence. In this paper we prove sufficient conditions for tightness of probability measures on $C_{\infty}(\Phi')$ and for weak convergence
arxiv  

Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner

open access: yesJournal of experimental & clinical cancer research : CR, 2019
Metabolic reprogramming is one of the hallmarks of cancer cells. The pentose phosphate pathway (PPP), a branch of glycolysis, is an important metabolic pathway for the survival and biosynthesis of cancer cells.
Zhaoyu Qin   +9 more
semanticscholar   +1 more source

Novel localization of formin mDia2: importin β-mediated delivery to and retention at the cytoplasmic side of the nuclear envelope

open access: yesBiology Open, 2015
The formin family proteins are important regulators of actin polymerization that are involved in many cellular processes. However, little is known about their specific cellular localizations.
Xiaowei Shao   +3 more
doaj   +1 more source

Quantum Description of Nuclear Spin Cooling in a Quantum Dot [PDF]

open access: yesPhys. Rev. B 75, 155324 (2007), 2006
We study theoretically the cooling of an ensemble of nuclear spins coupled to the spin of a localized electron in a quantum dot. We obtain a master equation for the state of the nuclear spins interacting with a sequence of polarized electrons that allows us to study quantitatively the cooling process including the effect of nuclear spin coherences ...
arxiv   +1 more source

Probing the Specificity of Binding to the Major Nuclear Localization Sequence-binding Site of Importin-α Using Oriented Peptide Library Screening*

open access: yesJournal of Biological Chemistry, 2010
Importin-α is the nuclear import receptor that recognizes the classic monopartite and bipartite nuclear localization sequences (cNLSs), which contain one or two clusters of basic amino acids, respectively.
Sundy N. Y. Yang   +5 more
semanticscholar   +1 more source

Sequences enriched in Alu repeats drive nuclear localization of long RNAs in human cells

open access: yesNature, 2017
Long noncoding RNAs (lncRNAs) are emerging as key parts of multiple cellular pathways, but their modes of action and how these are dictated by sequence remain unclear.
Yoav Lubelsky, I. Ulitsky
semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

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