Results 41 to 50 of about 3,441,532 (219)

NMR Studies on the Structure of Yeast Sis1 and the Dynamics of Its Interaction with Ssa1-EEVD

Molecules
HSP70 chaperones play pivotal roles in facilitating protein folding, refolding, and disaggregation through their binding and releasing activities. This intricate process is further supported by J-domain proteins (JDPs), also known as DNAJs or HSP40s ...
Carolina O. Matos, Glaucia M. S. Pinheiro, Icaro P. Caruso, Gisele C. Amorim, Fabio C. L. Almeida, Carlos H. I. Ramos   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The nature and impacts of fines in smelter-grade alumina [PDF]

, 2009
Fines in smelter-grade aluminas art recognized (is a significant process problem in aluminum smelting. However understanding the nature of this fine material and how it impacts the reduction process arc, less clearly understood The combination of new ...
Zujovic, Zoran D., Perander, Linus M., Kemp, Thomas F., Smith, Mark E., Metson, James B.   +4 more
core   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Conformational Switching of Proteins on Material Surfaces Enabled by Peptide‐Oriented Adsorption

Advanced Functional Materials, EarlyView.
Responsive biointerfaces could be achieved using conformationally responsive proteins; however, their interconversion can be lost upon surface adsorption. Herein, we demonstrate that the incorporation a Au binding peptide into calmodulin allows for binding control on Au wherein the protein retains conformational switching. This capability was confirmed
Sakthirupini Ramamurthy, Kyle B. Meerbott, Lorenzo Travaglini, Garima S. Dobhal, Artur Sawicki, Marc R. Knecht, Tiffany R. Walsh, Dominic J. Glover   +7 more
wiley   +1 more source

K48-ubiquitin-dependent proteases cut-up post-ER proteins

Nature Communications
Polyubiquitin chains, linked via K48 or K63 of ubiquitin, direct membrane proteins in the secretory system to distinct degradative fates. However, it’s unclear whether these linkage isomers are functionally interchangeable.
Annabel Y. Minard, Stanley Winistorfer, Liping Yu, Robert C. Piper   +3 more
doaj   +1 more source

Molecular Thermodynamics Using Nuclear Magnetic Resonance (NMR) Spectroscopy

Inventions, 2019
Nuclear magnetic resonance (NMR) spectroscopy is perhaps the most widely used technology from the undergraduate teaching labs in organic chemistry to advanced research for the determination of three-dimensional structure as well as dynamics of ...
Viswanathan V. Krishnan
doaj   +1 more source

Introduction to nuclear magnetic resonance

, 2011
Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful non-invasive analytical method that is gaining popularity in recent years due to its wide range of applications in various fields of research.
William S. Price, Allan M. Torres, Price, William S. (R10381), Torres, Allan M. (R11665)   +3 more
core   +1 more source

Particle‐Level ZrO2 Atomic Layer Deposition Enables Fast‐Cycling and Long‐Life Graphite Cathodes for Dual‐Ion Batteries

Advanced Functional Materials, EarlyView.
A spatial location of atomic layer deposition (ALD)‐derived ZrO2 coatings is demonstrated to be a critical design parameter for stabilizing graphite cathodes in DIBs. Direct particle‐level ALD (PALD) screening of representative metal oxides identified ZrO2 as the coating that provides the most favorable balance of high‐rate capability and interfacial ...
Jieun Kang, Sung Eun Jo, Yunah Ji, Dongjoo Kim, Sungho Kim, Jaegeon Ryu, Jihwan An, Soojin Park   +7 more
wiley   +1 more source