In situ nuclear matrix preparation in Drosophila melanogaster embryos/tissues and its use in studying the components of nuclear architecture. [PDF]
The study of nuclear matrix (NuMat) over the last 40 years has been limited to either isolated nuclei from tissues or cells grown in culture. Here, we provide a protocol for NuMat preparation in intact Drosophila melanogaster embryos and its use in ...
Pathak RU +4 more
europepmc +2 more sources
Major Virion Tegument Protein VP22 Targets Nuclear Matrix and Chromatin upon Entry into Cells during Productive Herpes Simplex Virus 1 Infection. [PDF]
HSV-1 major tegument protein VP22 is present in multiple subcellular locations in the late stages of productive viral infection. We initially performed a detailed time course experiment and observed that VP22 was detected in nuclear and nuclear matrix ...
Chi I, Blaho JA.
europepmc +2 more sources
Nuclear matrix associated RNAs in posterior silk glands show developmental dynamics in Bombyx mori in 5th instar larvae. [PDF]
Objectives The nuclear matrix maintains and regulates chromatin structure. RNA is an integral component of the nuclear matrix and is essential to its structural maintenance.
Chunduri AR +3 more
europepmc +2 more sources
Chromatin attachment to the nuclear matrix represses hypocotyl elongation in Arabidopsis thaliana. [PDF]
The nuclear matrix is a nuclear compartment that has diverse functions in chromatin regulation and transcription. However, how this structure influences epigenetic modifications and gene expression in plants is largely unknown.
Xu L +10 more
europepmc +2 more sources
Nuclear matrix associated RNA datasets of posterior silk glands of Bombyx mori during 5th instar larval development. [PDF]
Objectives Bombyx mori is the key contributor to industrial silk production. The maximum production of silk occurs during 5th instar. The posterior silk glands in the larvae are responsible for the production of the main component of silk fibre—fibroin ...
Chunduri AR +3 more
europepmc +2 more sources
Nuclear matrix revisited? [PDF]
In recent years a series of exciting discoveries, largely based on potent global genomic technologies, have profoundly changed our understanding of the mechanisms underlying integrated transcriptional programs. For example, genetic and genomic approaches to study the 3-dimensional organization of the genome at increasing resolution have suggested the ...
Skowronska-Krawczyk D, Rosenfeld MG.
europepmc +6 more sources
CIZ1 in Xist seeded assemblies at the inactive X chromosome
There is growing evidence that X-chromosome inactivation is driven by phase-separated supramolecular assemblies. However, among the many proteins recruited to the inactive X chromosome by Xist long non-coding RNA, so far only a minority (CIZ1, CELF1 ...
Sajad Sofi, Dawn Coverley, Dawn Coverley
doaj +1 more source
The elusive nuclear matrix [PDF]
The structure of the interphase nucleus is a major area of current interest in cell biology. It is thought likely that the nucleus is organised around some form of structural matrix and that this matrix will play a role in processes as diverse as chromosome replication and the integration of gene expression.
R S, Jack, H, Eggert
openaire +2 more sources
Lymphocytes’ ‘last stand’ on the nuclear matrix after whole body exposure of rats to low-let ionizing radiation [PDF]
We examined the functions of the rat lymphocyte nuclear matrix after a single exposure to total body irradiation with doses ranging from sublethal to lethal.
Martinović Vesna I. +5 more
doaj +1 more source
Dynamic associations of transcription factors with the rat liver nuclear matrix are functionally related to differential alpha-2-macroglobulin gene expression [PDF]
Participation of the nuclear matrix in regulation of alpha-2-macroglobulin (α2M) gene transcription during rat liver development and the acute-phase (AP) response are examined.
Dinić Svetlana +6 more
doaj +1 more source

