Results 71 to 80 of about 940,247 (326)

The policies of the United States towards the Indian and the Pakistani nuclear weapons programs [PDF]

open access: yes, 2002
The study is about the US policies towards the Indian and the Pakistani nuclear weapons programs in 1945-2001. In addition to the two nuclear weapons programs and the reasons behind them, also US policies towards them and the factors that have ...
Lahti, Makreeta
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Atlanta Consultation II: On the Future of the NPT [PDF]

open access: yes, 2005
The Middle Powers Initiative, a program of the Global Security Institute, organized an Extraordinary Strategy Consultation on the Nuclear Non-proliferation Treaty (NPT) 2005 Review Conference in cooperation with former U.S.

core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

The Role of Nuclear Diplomacy

open access: yesAtom Indonesia, 2007
In the midst of nuclear countries and non-nuclear countries in the framework of non-proliferation and disarmament, Indonesia has played an important role.
S. Sriwidjaja
doaj   +1 more source

Australia and the Non-Proliferation and Disarmament Initiative: difficult times for disarmament diplomacy [PDF]

open access: yes
Australia recognises the critical role that the Treaty on the Non-Proliferation of Nuclear Weapons plays in preventing uncontrolled proliferation and promoting disarmament, and upholding the treaty has long been a core foreign policy goal.
Tanya Ogilvie-White
core  

North Korea and the Non-proliferation Regime [PDF]

open access: yes, 2009
In this review of the implications of North Korea’s behaviour during 2009 on the Non-proliferation Regime, it is stressed that if North Korea cannot be deterred from its nuclear ambitions this will deliver a serious blow to the international non ...
Reiss, Mitchell B.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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