Results 81 to 90 of about 699,479 (309)

Finland and Nuclear Non-Proliferation : Fifty years of implementing the Nuclear Non-Proliferation Treaty [PDF]

, 2020
The research paper by Petri Paju, Adjunct Professor at the University of Turku, explores the methods of and motives for Finns implementing the Nuclear Non-Proliferation Treaty from the 1960s onwards.
Paju, Petri
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The Use of the Internet and ICT to Monitor Uranium Enrichment Programmes and Contrast Nuclear Proliferation

, 2013
The speech illustrated the possibility of using cyberspace to counter nuclear proliferation. In particular, the issue was discussed in relation to the (un)lawful status of cyberspace operations under international ...
Annachiara Rotondo
core  

Multilateral Nuclear Approaches

Meridiano 47, 2017
Calls for Multilateral Nuclear Approaches (MNAs) have been raised due to growing risks that the expansion of the nuclear power sector poses to a strained international non-proliferation regime.
Rodrigo Moreira Penna
doaj  

The Treaty on the Prohibition of Nuclear Weapons: Strengths, Weaknesses and Current Status

Journal for Peace and Nuclear Disarmament
This commentary offers an analysis of the Treaty on the Prohibition of Nuclear Weapons (TPNW), its strengths, weaknesses, relationship to other agreements as well as recent updates.
Jean Krasno, Elisabeth Szeli
doaj   +1 more source

The Role of Nuclear Diplomacy

Atom Indonesia, 2007
In the midst of nuclear countries and non-nuclear countries in the framework of non-proliferation and disarmament, Indonesia has played an important role.
S. Sriwidjaja
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

U.S. support for peaceful nuclear cooperation.

, 2000
"April 2000"--P.
United States. Non-Proliferation Bureau. Multilateral Nuclear Affairs.
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

The EU and Iran’s Nuclear Programme: Testing the Limits of Coercive Diplomacy. College of Europe EU Diplomacy Paper 1/2009 [PDF]

, 2009
The paper analyzes the E-3’s/EU’s diplomatic strategy vis-à-vis Iran and its nuclear programme against the theoretical background of coercive diplomacy.
Tocha, Monika.
core