Results 71 to 80 of about 699,479 (309)
Civil society legitimacy and nuclear non-proliferation [PDF]
During recent years, civil society legitimacy has generated a growing interest in scholarly research. The present article therefore proposes four normative criteria, namely, independence, transparency, participation, and inclusion, in order to start ...
Kissling, Claudia
core
Investigation of nuclear material using a compact modified uniformly redundant array gamma camera
Nuclear Engineering and Technology, 2018 We developed a compact gamma camera based on a modified uniformly redundant array coded aperture to investigate the position of a UO2 pellet emitting characteristic X-rays (98.4 keV) and γ-rays (185.7 keV).
Taewoong Lee, Sung-Woo Kwak, Wonho Lee
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Best Practice Guidelines for Cooperative Compliance with Nuclear Non-Proliferation Obligations [PDF]
, 2015 peer reviewedThe role of the law in front of nuclear technologies and nuclear weapons is a meaningful one. The law is aimed to regulate the existing nuclear activities, or – at a preliminary stage – to (try to) prevent and govern the risks arising from ...
Colussi, I. A. +4 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Em nome da autonomia e do desenvolvimento
Meridiano 47, 2017 The objective is to examine the positions adopted by Brazil on nuclear non-proliferation, disarmament and peaceful uses of nuclear energy in the beginning of this century.
Diego Santos Vieira de Jesus
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The global nuclear order and the crisis of the nuclear non-proliferation regime: Taking stock and moving forward. [PDF]
Z Friedens Konfliktforsch, 2021 Baldus J, Müller H, Wunderlich C.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Sanctions, statecraft, and nuclear proliferation
, 2012 Some states have violated international commitments not to develop nuclear weapons. Yet the effects of international sanctions or positive inducements on their internal politics remain highly contested.
core +1 more source