Results 121 to 130 of about 2,248,811 (276)

Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold

Science, 2022
P. Fontana, Ying Dong, X. Pi, A. Tong, Corey W. Hecksel, Longfei Wang, T. Fu, Carlos D. Bustamante, Hao Wu   +8 more
semanticscholar   +1 more source

Nuclear Pore-Like Structures in a Compartmentalized Bacterium.

PLoS ONE, 2017
Planctomycetes are distinguished from other Bacteria by compartmentalization of cells via internal membranes, interpretation of which has been subject to recent debate regarding potential relations to Gram-negative cell structure.
Evgeny Sagulenko, Amanda Nouwens, Richard I Webb, Kathryn Green, Benjamin Yee, Garry Morgan, Andrew Leis, Kuo-Chang Lee, Margaret K Butler, Nicholas Chia, Uyen Thi Phuong Pham, Stinus Lindgreen, Ryan Catchpole, Anthony M Poole, John A Fuerst   +14 more
doaj   +1 more source

Post-translational O-GlcNAcylation is essential for nuclear pore integrity and maintenance of the pore selectivity filter.

Journal of Molecular Cell Biology, 2016
O-glycosylation of the nuclear pore complex (NPC) by O-linked N-acetylglucosamine (O-GlcNAc) is conserved within metazoans. Many nucleoporins (Nups) comprising the NPC are constitutively O-GlcNAcylated, but the functional role of this modification ...
Yanping Zhu, Ta-Wei Liu, Zarina Madden, S. Yuzwa, Kelsey D Murray, Samy Cecioni, N. Zachara, D. Vocadlo   +7 more
semanticscholar   +1 more source

Nup133 Is Required for Proper Nuclear Pore Basket Assembly and Dynamics in Embryonic Stem Cells

Cell Reports, 2018
Summary: Nup133 belongs to the Y-complex, a key component of the nuclear pore complex (NPC) scaffold. Studies on a null mutation in mice previously revealed that Nup133 is essential for embryonic development but not for mouse embryonic stem cell (mESC ...
Benoit Souquet, Ellen Freed, Alessandro Berto, Vedrana Andric, Nicolas Audugé, Bernardo Reina-San-Martin, Elizabeth Lacy, Valérie Doye   +7 more
doaj  

Nuclear pore complexes — a doorway to neural injury in neurodegeneration

Nature Reviews Neurology, 2022
Alyssa N. Coyne, J. Rothstein
semanticscholar   +1 more source

In situ structural analysis of the human nuclear pore complex

Nature, 2015
Nuclear pore complexes are fundamental components of all eukaryotic cells that mediate nucleocytoplasmic exchange. Determining their 110-megadalton structure imposes a formidable challenge and requires in situ structural biology approaches.
Alexander von Appen, J. Kosiński, Lenore Sparks, A. Ori, Amanda L. DiGuilio, B. Vollmer, Marie-Therese Mackmull, N. Banterle, L. Parca, P. Kastritis, K. Buczak, S. Mosalaganti, W. Hagen, A. Andres-Pons, E. Lemke, P. Bork, Wolfram Antonin, J. Glavy, K. Bui, Martin Beck   +19 more
semanticscholar   +1 more source

Comparative study on pore size distribution in coal based on mercury intrusion-low temperature liquid nitrogen combined pore and nuclear magnetic resonance analysis

Meikuang Anquan
The pore structure measurement in coal is commonly analyzed by mercury intrusion method, low temperature liquid nitrogen method and nuclear magnetic resonance method. Due to the different test methods, the results cannot be used uniformly, and the matrix
Nana LI, Huihu LIU, Shuxun SANG
doaj   +1 more source

Energetics of Transport through the Nuclear Pore Complex

PLoS ONE, 2016
Molecular transport across the nuclear envelope in eukaryotic cells is solely controlled by the nuclear pore complex (NPC). The NPC provides two types of nucleocytoplasmic transport: passive diffusion of small molecules and active chaperon-mediated ...
Ali Ghavami, E. van der Giessen, P. Onck
semanticscholar   +1 more source

Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore

eLife, 2018
Non-centrosomal microtubule organizing centers (MTOCs) are important for microtubule organization in many cell types. In fission yeast Schizosaccharomyces pombe, the protein Mto1, together with partner protein Mto2 (Mto1/2 complex), recruits the γ ...
Xun X Bao, Christos Spanos, Tomoko Kojidani, Eric M Lynch, Juri Rappsilber, Yasushi Hiraoka, Tokuko Haraguchi, Kenneth E Sawin   +7 more
doaj   +1 more source

The selective permeability barrier in the nuclear pore complex

The Nucleus, 2016
The nuclear pore complex (NPC) mediates the shuttle transport of macromolecules between the nucleus and cytoplasm in eukaryotic cells. The permeability barrier formed by intrinsically disordered phenylalanine-glycine-rich nucleoporins (FG-Nups) in the ...
Christina Li, Alexander Goryaynov, Weidong Yang   +2 more
semanticscholar   +1 more source