Results 141 to 150 of about 2,343,531 (340)

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Nuclear Pore-Like Structures in a Compartmentalized Bacterium.

open access: yesPLoS ONE, 2017
Planctomycetes are distinguished from other Bacteria by compartmentalization of cells via internal membranes, interpretation of which has been subject to recent debate regarding potential relations to Gram-negative cell structure.
Evgeny Sagulenko   +14 more
doaj   +1 more source

Exportins can inhibit major mitotic assembly events in vitro: membrane fusion, nuclear pore formation, and spindle assembly

open access: yesNucleus, 2020
Xenopus egg extracts are a powerful in vitro tool for studying complex biological processes, including nuclear reconstitution, nuclear membrane and pore assembly, and spindle assembly.
Matthew S. Nord   +5 more
doaj   +1 more source

NMR Based Diffusion Pore Imaging by Double Wave Vector Measurements [PDF]

open access: yesarXiv, 2012
In porous material research, one main interest of nuclear magnetic resonance (NMR) diffusion experiments is the determination of the exact shape of pores. It has been a longstanding ques-tion if this is achievable in principle. In this work, we present a method using short diffusion gradient pulses only, which is able to reveal the shape of arbitrary ...
arxiv  

Multi-scale simulation of capillary pores and gel pores in Portland cement paste [PDF]

open access: yes, 2015
The microstructures of Portland cement paste (water to cement ratio is 0.4, curing time is from 1 day to 28 days) are simulated based on the numerical cement hydration model, HUMOSTRUC3D (van Breugel, 1991; Koenders, 1997; Ye, 2003).
Gao, Peng   +3 more
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

mSphere of Influence: the Dynamic Nature of the Nuclear Envelope during Mitosis of Malaria Parasites

open access: yesmSphere, 2020
Sabrina Absalon works in the field of cellular and molecular biology of Plasmodium falciparum, the most virulent parasite causing malaria in humans. In this mSphere of Influence article, she reflects on how the paper “3D nuclear architecture reveals ...
Sabrina Absalon
doaj   +1 more source

The nuclear pore complex as an entropic gate: theory and simulation [PDF]

open access: yesarXiv, 2020
Protein chains of the (FG)$_n$ ($n \simeq$ 300) type cap the cytoplasmatic side of the nucleopore complex, which connects the nucleus to the remainder of an eukaryotic cell. We study the properties of three fundamental polymer models that represent these filaments using Monte Carlo computer simulations. Random walks and the worm like chain model cannot
arxiv  

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Post-translational O-GlcNAcylation is essential for nuclear pore integrity and maintenance of the pore selectivity filter.

open access: yesJournal of Molecular Cell Biology, 2016
O-glycosylation of the nuclear pore complex (NPC) by O-linked N-acetylglucosamine (O-GlcNAc) is conserved within metazoans. Many nucleoporins (Nups) comprising the NPC are constitutively O-GlcNAcylated, but the functional role of this modification ...
Yanping Zhu   +7 more
semanticscholar   +1 more source

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