Results 291 to 300 of about 326,922 (335)
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1996
The nuclear envelope forms the boundary between the nucleus and the cytoplasm and as such regulates the exchange of macromolecules between the two compartments. The channels through the nuclear envelop that actually mediate this macromolecular traffic are the nuclear pore complexes.
R, Bastos, N, Panté, B, Burke
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The nuclear envelope forms the boundary between the nucleus and the cytoplasm and as such regulates the exchange of macromolecules between the two compartments. The channels through the nuclear envelop that actually mediate this macromolecular traffic are the nuclear pore complexes.
R, Bastos, N, Panté, B, Burke
openaire +2 more sources
Nuclear transport and nuclear pores in yeast
Antonie van Leeuwenhoek, 1992The central features of nuclear import have been conserved during evolution. In yeast the nuclear accumulation of proteins follows the same selective and active transport mechanisms known from higher eukaryotes. Yeast nuclear proteins contain nuclear localization sequences (NLS) which are presumably recognized by receptors in the cytoplasm and the ...
U, Nehrbass, E C, Hurt
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Solving the nuclear pore puzzle
Science, 2022Using a battery of tools, the architecture of the nuclear pore complex is ...
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Pore relations: nuclear pore complexes and nucleocytoplasmic exchange
Essays in Biochemistry, 2000NPCs are the sole sites of exchange between the nucleus and cytoplasm. A large family of transport factors carry cargo between the nucleus and cytoplasm through the NPC. The NPC is a huge symmetric octagonal structure comprised of dozens of NUPs. NUPs make many contacts with surrounding structures, including the NE, the cytoplasm and nuclear interior ...
M P, Rout, J D, Aitchison
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Poring over chromosomes: mitotic nuclear pore complex segregation
Current Opinion in Cell Biology, 2019Eukaryotic cells rely on flux of macromolecules between the nucleus and the cytoplasm for growth and survival. Bidirectional transport is achieved through Nuclear Pore Complexes (NPCs) embedded in the Nuclear Envelope (NE). NPC proteins perform other cellular functions during mitosis, chromatin organization, DNA repair and gene regulation ...
Subbulakshmi, Suresh, Stephen A, Osmani
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Nuclear pores. Architecture of the nuclear pore complex coat.
Science (New York, N.Y.), 2015The nuclear pore complex (NPC) constitutes the sole gateway for bidirectional nucleocytoplasmic transport. Despite half a century of structural characterization, the architecture of the NPC remains unknown. Here we present the crystal structure of a reconstituted ~400-kilodalton coat nucleoporin complex (CNC) from Saccharomyces cerevisiae at a 7.4 ...
Tobias, Stuwe +6 more
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2010
Nuclear pore complexes (NPCs) are large macromolecular assemblies with an estimated mass of about 125 million Dalton. Depending on the activity of a cell, the number of NPCs varies but is usually around 3000–4000 per nucleus. NPCs are sites of bidirectional transport.
Margit Pavelka, Jürgen Roth
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Nuclear pore complexes (NPCs) are large macromolecular assemblies with an estimated mass of about 125 million Dalton. Depending on the activity of a cell, the number of NPCs varies but is usually around 3000–4000 per nucleus. NPCs are sites of bidirectional transport.
Margit Pavelka, Jürgen Roth
openaire +1 more source
Pore-scale modeling of complex transport phenomena in porous media
Progress in Energy and Combustion Science, 2022Li Chen, An He, Jianlin Zhao
exaly
Gasdermin D pore structure reveals preferential release of mature interleukin-1
Nature, 2021Shiyu Xia +2 more
exaly