Abstract Purpose Stereotactic radiotherapy (SRT) is a highly effective treatment with precision for small, localized lesions. Proton therapy, characterized by the Bragg peak, offers superior dose conformity compared to photon‐based approaches. However, challenges remain in minimizing lateral penumbra and optimizing dose delivery, particularly for small
Chen‐Yu Chou+3 more
wiley +1 more source
Radiotherapy medical physics in the Philippines: A contemporary overview
Abstract Purpose With cancer ranking as the third leading cause of death in the Philippines and a disparity in healthcare resources across regions, this research aimed to assess the state of radiotherapy medical physics in the country. Methodology The study utilized a comprehensive online survey with 94 structured questions answered by 19 clinics ...
John Paul C. Cabahug+4 more
wiley +1 more source
Mitochondrial DNA disorders in neuromuscular diseases in diverse populations
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao+34 more
wiley +1 more source
Nanoscale interactions of arginine-containing dipeptide repeats with nuclear pore complexes as measured by transient scanning electrochemical microscopy. [PDF]
Huang SH+4 more
europepmc +1 more source
Abstract Objective Exploring the prevalence and association between intracranial atherosclerosis (ICAS) and cerebral small vessel diseases (CSVD), this study delved beyond the current scope, utilising high‐resolution vessel wall MRI (HRVW‐MRI) to investigate how subtle changes in intracranial atherosclerotic features influence the various burdens of ...
Joseph Amihere Ackah+6 more
wiley +1 more source
Single nucleotide variants in nuclear pore complex disassembly pathway associated with poor survival in osteosarcoma. [PDF]
Jacobs JE, Davis L, McWeeney S.
europepmc +1 more source
Nuclear pore pathology underlying multisystem proteinopathy type 3-related inclusion body myopathy. [PDF]
Izumi R+10 more
europepmc +1 more source
SARS-CoV-2 Orf6 is positioned in the nuclear pore complex by Rae1 to inhibit nucleocytoplasmic transport. [PDF]
Makio T+9 more
europepmc +1 more source
Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ. [PDF]
Yu Y+12 more
europepmc +1 more source
CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly
Mathiowetz AJ+20 more
europepmc +1 more source