Results 311 to 320 of about 294,484 (344)
Some of the next articles are maybe not open access.
Autoantigens of the nuclear pore complex
Journal of Molecular Medicine, 2004The nuclear envelope (NE) is one of many intracellular targets of the autoimmune response in patients with autoimmune liver disease, systemic lupus erythematosus, and related conditions. In eukaryotic organisms the NE consists of five interconnected regions: an outer nuclear membrane (ONM) that is continuous with the endoplasmic reticulum, an ...
P, Enarson +5 more
openaire +2 more sources
Nuclear pore complex ion channels (Review)
Molecular Membrane Biology, 1994It is currently thought that nuclear pore complexes (NPCs) primarily govern nucleocytoplasmic interactions via selective recognition and active transport of macromolecules. However, in various nuclear preparations, patch-clamp and fluorescence, luminiscence and ion microscopy support classical microelectrode measurements indicating that monoatomic ion ...
J O, Bustamante +2 more
openaire +2 more sources
Cancer and the Nuclear Pore Complex
2014The nuclear pore complex (NPC) mediates trafficking between the cytoplasm and nucleoplasm. It also plays key roles in other nuclear processes such as chromatin silencing, transcriptional regulation, and DNA damage repair. Nucleoporins, the structural components of the NPC, have been linked to a multitude of cancers through chromosomal translocations ...
Dan N, Simon, Michael P, Rout
openaire +2 more sources
Nuclear pores. Architecture of the nuclear pore complex coat.
Science (New York, N.Y.), 2015The nuclear pore complex (NPC) constitutes the sole gateway for bidirectional nucleocytoplasmic transport. Despite half a century of structural characterization, the architecture of the NPC remains unknown. Here we present the crystal structure of a reconstituted ~400-kilodalton coat nucleoporin complex (CNC) from Saccharomyces cerevisiae at a 7.4 ...
Tobias, Stuwe +6 more
openaire +1 more source
Pore-scale modeling of complex transport phenomena in porous media
Progress in Energy and Combustion Science, 2022Li Chen, An He, Jianlin Zhao
exaly
Gasdermin D pore structure reveals preferential release of mature interleukin-1
Nature, 2021Shiyu Xia +2 more
exaly