Results 341 to 350 of about 805,782 (407)
In situ architecture of the nuclear pore complex of the higher plant Arabidopsis thaliana
Germain H+5 more
europepmc +1 more source
Pathway Analyses of Inherited Neuropathies Identify Putative Common Mechanisms of Axon Degeneration
ABSTRACT Objective Inherited neuropathies (IN) are associated with over 100 different genetic mutations presenting with a variety of phenotypes. This complexity suggests multiple pathways may converge onto a limited number of downstream pathways to effect axonal injury.
Christopher R. Cashman+2 more
wiley +1 more source
Super-resolution 3D tomography of interactions and competition in the nuclear pore complex
Jiong Ma+2 more
semanticscholar +1 more source
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone+19 more
wiley +1 more source
Yi‐Fei‐Jie‐Du‐Tang (YFJDT), a traditional Chinese medicine, has shown potential in lung cancer treatment by targeting key pathways. This study explores the mechanisms of YFJDT using bioinformatics, xenograft models, and A549 cells, demonstrating that YFJDT downregulates HIF1A, promotes ferroptosis, and inhibits epithelial‐mesenchymal transition (EMT ...
Shanshan Wang+6 more
wiley +1 more source
Super-Resolution Microscopy Gives New Insights into Nuclear Pore Complex Organization
doaj +1 more source
The small GTPase Ran defines Nuclear Pore Complex Asymmetry
Sachweh J+11 more
europepmc +1 more source
Protocol for live-cell super-resolution imaging of transport of pre-ribosomal subunits through the nuclear pore complex. [PDF]
Tingey M, Junod SL, Rush C, Yang W.
europepmc +1 more source
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe+4 more
wiley +1 more source