Results 161 to 170 of about 6,030,389 (286)

Transition nuclear protein 1 as a novel biomarker in patients with fertilization failure. [PDF]

Clin Exp Reprod Med, 2023
Mirsanei JS, Gholipour H, Zandieh Z, Jahromi MG, Masroor MJ, Mehdizadeh M, Amjadi F.   +6 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

An Early-Stage Nuclear Protein in Testis Carcinoma of the Lung in an Older Woman. [PDF]

Interdiscip Cardiovasc Thorac Surg
Shan G, Zeng D, Huang W, Yao G.
europepmc   +1 more source

Cutaneous metastasis of nuclear protein of the testis carcinoma: A new presentation of a rare entity. [PDF]

JAAD Case Rep, 2023
Toker M, Jaller JA, Srivastava P, Gersten AJ, Amin B, Mordorski B.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Imaging manifestations of nuclear protein in testis carcinoma in the maxillary sinus with elevated alpha-fetoprotein: a case description and literature analysis. [PDF]

Quant Imaging Med Surg
Zhang Y, Liu Y.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Nuclear protein 1 is a cell death regulator in primary human airway epithelial cells and reduced in idiopathic pulmonary fibrosis. [PDF]

Sci Rep
Zöller M, Mastalerz M, Dick E, Merl-Pham J, Hennen E, Prakki SRS, Chakraborty A, Nakayama M, Klotz M, Marchi H, LeGleut R, De Sadeleer LJ, Wuyts WA, Vanaudenaerde BM, Jeridi A, Prasse A, Jäger B, Santofimia-Castaño P, Stoleriu MG, Hilgendorff A, Hauck SM, Yildirim AÖ, Schiller H, Staab-Weijnitz CA.   +23 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

A Rare Case of Mediastinal NUT (Nuclear Protein in Testis) Carcinoma Presenting with Acute Respiratory Failure: A Case Report. [PDF]

Int Med Case Rep J
Javed H, Ahmad A, Rehman A, Mikula MW.
europepmc   +1 more source