Results 1 to 10 of about 3,298,558 (257)
Signaling Pathways in Pregnancy [PDF]
Cells, 2022 We are pleased to present this Special Issue of Cells, entitled ‘Signaling Pathways in Pregnancy’ [...]
Giovanni Tossetta, Daniela Marzioni
doaj +2 more sources
Conserved immunomodulatory transcriptional networks underlie antipsychotic-induced weight gain
Translational Psychiatry, 2021 Although antipsychotics, such as olanzapine, are effective in the management of psychiatric conditions, some patients experience excessive antipsychotic-induced weight gain (AIWG).
Rizaldy C. Zapata +6 more
doaj +1 more source
Signaling Pathways Involved in Rheumatoid Arthritis: Targets for New Therapeutic Interventions
NUST Journal of Natural Sciences, 2021 Rheumatoid arthritis is categorized as a systematic autoimmune disease which causes chronic disabilities exclusively in bones that are aligned with synovium.
Abdul Haseeb Khan +8 more
doaj +1 more source
Changes of Signaling Pathways in Hypothalamic Neurons with Aging
Current Issues in Molecular Biology, 2023 The hypothalamus is an important regulator of autonomic and endocrine functions also involved in aging regulation. The aging process in the hypothalamus is accompanied by disturbed intracellular signaling including insulin/insulin-like growth factor-1 ...
Petr M. Masliukov
doaj +1 more source
Retroactive signaling in short signaling pathways. [PDF]
PLoS ONE, 2012 In biochemical signaling pathways without explicit feedback connections, the core signal transduction is usually described as a one-way communication, going from upstream to downstream in a feedforward chain or network of covalent modification cycles. In
Jacques-Alexandre Sepulchre +2 more
doaj +1 more source
Frontiers in Oncology, 2022 Granulocyte colony-stimulating factor receptor (GCSFR) is a critical regulator of granulopoiesis. Studies have shown significant upregulation of GCSFR in a variety of cancers and cell types and have recognized GCSFR as a cytokine receptor capable of ...
Sungjin David Park +5 more
doaj +1 more source
Influence of Long Non-Coding RNA in the Regulation of Cancer Stem Cell Signaling Pathways
Cells, 2022 Over the past two decades, cancer stem cells (CSCs) have emerged as an immensely studied and experimental topic, however a wide range of questions concerning the topic still remain unanswered; in particular, the mechanisms underlying the regulation of ...
Kevina Sonawala +2 more
doaj +1 more source
Signaling Pathways Regulating Thermogenesis
Frontiers in Endocrinology, 2021 Obesity, an excess accumulation of white adipose tissue (WAT), has become a global epidemic and is associated with complex diseases, such as type 2 diabetes and cardiovascular diseases.
Chihiro Tabuchi, Hei Sook Sul
doaj +1 more source
Moonlight functions of glycolytic enzymes in cancer
Frontiers in Molecular Biosciences, 2023 Since an extensive genome research has started, basic principle “one gene—one protein—one function” was significantly revised. Many proteins with more than one function were identified and characterized as “moonlighting” proteins, which activity depend ...
Petr V. Shegay +9 more
doaj +1 more source
Deregulation of Interferon Signaling in Malignant Cells
Pharmaceuticals, 2010 Interferons (IFNs) are a family of cytokines with potent antiproliferative, antiviral, and immunomodulatory properties. Much has been learned about IFNs and IFN-activated signaling cascades over the last 50 years. Due to their potent antitumor effects in
Leonidas C. Platanias +2 more
doaj +1 more source