Results 31 to 40 of about 3,298,558 (257)

The Role of Curcumin in Cancer Treatment

Biomedicines, 2021
Curcumin is a polyphenol extracted from the rhizomes of the turmeric plant, Curcuma longa which has anti-inflammatory, and anticancer properties. Chronic inflammation is associated with the development of cancer.
Vasiliki Zoi, Vasiliki Galani, Georgios D. Lianos, Spyridon Voulgaris, Athanasios P. Kyritsis, George A. Alexiou   +5 more
doaj   +1 more source

Exercise-induced signaling pathways to counteracting cardiac apoptotic processes

Frontiers in Cell and Developmental Biology, 2022
Cardiovascular diseases are the most common cause of death in the world. One of the major causes of cardiac death is excessive apoptosis. However, multiple pathways through moderate exercise can reduce myocardial apoptosis.
Hamed Alizadeh Pahlavani
doaj   +1 more source

Towards a reporter system to identify regulators of cross-talk between salicylate and jasmonate signaling pathways in Arabidopsis [PDF]

, 2008
The plant signaling hormones salicylic acid (SA) and jasmonic acid (JA) are regulators of inducible defenses that are activated upon pathogen or insect attack.
van Loon, L.C., Koornneef, A., Pieterse, C.M.J., Loon, L.C. van, Snetselaar, R., Leon Reyes, H.A., Verhage, A.   +6 more
core   +1 more source

Cav1.2 Activity and Downstream Signaling Pathways in the Hippocampus of An Animal Model of Depression [PDF]

, 2020
Functional and morphological modifications in the brain caused by major mood disorders involve many brain areas, including the hippocampus, leading to cognitive and mood alterations.
Víctor Aballai, Hardy, Paulina, Cristian Moreno, Rojas, Patricio, Paulina Hardy, Moreno, Cristian, Hermosilla, Tamara, Aballai, Víctor, Patricio Rojas, Diego Varela, Varela Lekanda, Diego, Tamara Hermosilla   +11 more
core   +1 more source

Toll-like receptor signaling pathways

Frontiers in Immunology, 2014
Toll-like receptors (TLRs) play crucial roles in the innate immune system by recognizing pathogen-associated molecular patterns derived from various microbes. TLRs signal through the recruitment of specific adaptor molecules, leading to activation of the
Taro eKawai, Takumi eKawasaki
doaj   +1 more source

Integrated analysis of microRNA and mRNA expression profiles in Preeclampsia

BMC Medical Genomics, 2023
Background Preeclampsia (PE), a pregnancy specific syndrome, is one kind of common gestational hypertension disease, which can cause maternal and perinatal mortality and morbidity.
Zepeng Ping, Ying Feng, Ying Lu, Ling Ai, Huling Jiang   +4 more
doaj   +1 more source

Downregulation of Interleukin-13 Receptor α2 Inhibits Angiogenic Formation Mediated by Chitinase 3-Like 1 in Late Atherosclerotic Lesions of apoE−/− Mice

Frontiers in Physiology, 2021
Aim: Chitinase 3-like 1 (CHI3L1) has the potential to prompt proliferation and angiogenic formation. Interleukin-13 receptor α2 (IL-13Rα2) was regarded as a receptor of CHI3L1; however, it is unknown whether CHI3L1 adjusts the neovascularization in late ...
Qi Xue, Lei Chen, Jianwu Yu, Kewang Sun, Lifang Ye, Jianlei Zheng, Jianlei Zheng   +6 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Cardiac optogenetics: shining light on signaling pathways. [PDF]

, 2023
In the early 2000s, the field of neuroscience experienced a groundbreaking transformation with the advent of optogenetics. This innovative technique harnesses the properties of naturally occurring and genetically engineered rhodopsins to confer light ...
Schneider-Warme, Franziska, Leemann, Siri, Kleinlogel, Sonja   +2 more
core   +2 more sources

Bufalin Induces Apoptosis of Human Osteosarcoma U-2 OS Cells through Endoplasmic Reticulum Stress, Caspase- and Mitochondria-Dependent Signaling Pathways

Molecules, 2017
Bone cancer is one of the cancer-related diseases, and there are increased numbers of patients with bone cancer worldwide. Therefore the efficacy of treatment of bone cancer is considered extremely vital.
Ching-Hsiao Lee, Yung-Luen Shih, Mei-Hui Lee, Man-Kuan Au, Yung-Liang Chen, Hsu-Feng Lu, Jing-Gung Chung   +6 more
doaj   +1 more source