Results 181 to 190 of about 6,030,389 (286)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

A High-Throughput ImmunoHistoFluorescence (IHF) Method for Sub-Nuclear Protein Analysis in Tissue. [PDF]

Cells
Oxe KC, Rohrberg KS, Lassen U, Larsen DH.   +3 more
europepmc   +1 more source

Dysregulation of the progranulin-driven autophagy-lysosomal pathway mediates secretion of the nuclear protein TDP-43. [PDF]

J Biol Chem, 2023
Tanaka Y, Ito SI, Honma Y, Hasegawa M, Kametani F, Suzuki G, Kozuma L, Takeya K, Eto M.   +8 more
europepmc   +1 more source

Protein—protein interaction in the nuclear envelope

FEBS Letters, 1976
Cochran, David L., Shelton, Keith R.
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Nuclear Protein Aggregates Disrupt RNA Processing and Alter Biomechanics in a Muscle Cell Model of OPMD. [PDF]

Aging Dis
Shademan M, Flannery S, Bos E, Evers TMJ, Sheikhhassani V, Mashaghi A, Kusters B, van Engelen B, Sharp TH, Fischer R, Kessler BM, Raz V.   +11 more
europepmc   +1 more source

Dual targeting of protein translation and nuclear protein export results in enhanced antimyeloma effects. [PDF]

Blood Adv, 2023
Li S, Fu J, Walker CJ, Yang J, Bhutani D, Chakraborty R, Mamillapalli N, Mapara MY, Landesman Y, Lentzsch S.   +9 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Paired Analyses of Nuclear Protein Targets and Genomic DNA by Single-Cell Western Blot and Single-Cell PCR. [PDF]

Anal Chem
Gomez Martinez AE, Lam T, Herr AE.
europepmc   +1 more source

Nuclear protein quality control in yeast: The latest INQuiries. [PDF]

J Biol Chem, 2022
Kumar A, Kumar A, Mathew V, Stirling PC.
europepmc   +1 more source