PCNP promotes hepatocellular carcinoma progression by upregulating UHRF2 to activate ErbB3/Ras/Raf pathway [PDF]
Scientific ReportsThe PEST-containing nuclear protein (PCNP) has been reported to play paradoxical roles in tumorigenesis. While PCNP functions as a tumor suppressor in neuroblastoma and lung adenocarcinoma, it has been identified as a tumor promoter in ovarian cancer ...
Xiangyu Zhao
exaly +5 more sources
The role and potential mechanism of PEST-containing nuclear protein (PCNP) in endothelial cell angiogenesis in vitro [PDF]
Scientific ReportsRetinal neovascularization (RNV) is a pathological hallmark of vision-threatening diseases such as diabetic retinopathy. Current therapies targeting vascular endothelial growth factors (VEGF) have limitations, highlighting the need for novel therapeutic ...
Yalong Dang
exaly +5 more sources
LINC00858 promotes colon cancer progression through activation of STAT3/5 signaling by recruiting transcription factor RAD21 to upregulate PCNP [PDF]
Cell Death Discovery, 2022 The purpose of our investigation is to explore the putative molecular mechanisms underpinning LINC00858 involvement in colon cancer. The expression of LINC00858 in TCGA data was identified using the GEPIA website.
Shutao Zheng, Ting Xu, Baofei Jiang
exaly +5 more sources
Ethylene oligomerisation chromium catalysts with unsymmetrical PCNP ligands†
Dalton Transactions, 2021 PCNP diphosphines, in conjunction with Cr(acac) 3 , are excellent ethylene oligomerisation catalysts with high activity and selectivity towards both 1-hexene and 1-octene formation.
Mark R.J. Elsegood +2 more
exaly +11 more sources
Tissue mechanics modulate PCNP expression in oral squamous cell carcinomas with different differentiation [PDF]
Frontiers in Oncology, 2023 BackgroundPEST-containing nuclear protein (PCNP), a novel zinc finger protein, participates in cell cycle regulation. Previous studies have confirmed that PCNP plays a role in mediating cellular development and invasion in a variety of cancer types ...
Leyang Zhang +13 more
doaj +4 more sources
Taking a holistic view of PEST-containing nuclear protein (PCNP) in cancer biology [PDF]
Cancer Medicine, 2019 Polypeptide sequences enriched with proline (P), glutamic acid (E), aspartic acid (D) and serine (S)/ threonine (T) (PEST) have been reported to be the most abundant and frequently distributed at the cellular level.
Dongdong Wu, Attia Afzal, Xin-Ying Ji
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PCNP is a novel regulator of proliferation, migration, and invasion in human thyroid cancer [PDF]
International Journal of Biological Sciences, 2022 Thyroid cancer (TC) has increased globally, with a prominent increase in small, papillary thyroid cancers. PEST-containing nuclear protein (PCNP), a nuclear protein, has been found to be associated with human cancers in recent years. However, the role and molecular mechanism of PCNP in thyroid cancer remain underexplored.
Da-Yong Wang
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Biology of PEST‐Containing Nuclear Protein: A Potential Molecular Target for Cancer Research [PDF]
Frontiers in Oncology, 2022 PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in vital cellular processes like cell proliferation and mediates tumorigenesis.
Muhammad Shahid +2 more
exaly +4 more sources
Supplementation of nanoencapsulated Peronema canescens jack leaf extract on growth performance, carcass traits, digestive characteristics, and jejunum histomorphometry in broiler chickens [PDF]
Open Veterinary JournalBackground: Peronema canescens Jack (P. canescens) leaves contain phenols, tannins, flavonoids, and saponins with antibacterial, antioxidant, and growth-promoting activities. However, their lipophilic nature limits their absorption in broilers. Chitosan-
Bella Putri Maharani +8 more
doaj +2 more sources
Polycationic nanopeptide-fused endolysins for the control of Mannheimia haemolytica [PDF]
Applied Microbiology and BiotechnologyBovine respiratory disease (BRD) remains a major economic and animal health concern in cattle production, exacerbated by rising antimicrobial resistance and limited vaccine efficacy.
Sidra Moqaddes +9 more
doaj +2 more sources