Results 161 to 170 of about 1,731,332 (381)
Combining affinity purification and mass spectrometry to define the network of the nuclear proteins interacting with the N-terminal region of FMRP. [PDF]
Front Mol Biosci, 2022 Kieffer F +9 more
europepmc +1 more source
Transcriptional repression and cell death induced by nuclear aggregates of non-polyglutamine protein
Neurobiology of Disease, 2005 Nuclear aggregates of polyglutamine (polyQ)-expanded proteins are associated with a number of neurodegenerative diseases including Huntington's disease (HD) and spinocerebellar ataxias (SCAs).
Lianwu Fu, Ya-sheng Gao, Elizabeth Sztul
doaj
Methods to separate nuclear soluble fractions reflecting localizations in living cells
iScience, 2021 Summary: To understand various intranuclear functions, it is important to know when, what, and how proteins enter the nucleus. Although many methods and commercial kits for nuclear fractionation have been developed, there are still no methods for ...
Yutaka Ogawa, Naoko Imamoto
doaj
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Joint single-cell measurements of nuclear proteins and RNA in vivo. [PDF]
Nat Methods, 2021 Chung H +9 more
europepmc +1 more source
Effects of Basic Nuclear Proteins on Cardiac Muscle Function [PDF]
, 1965 Arnold Schwartz +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
NEAT-seq: simultaneous profiling of intra-nuclear proteins, chromatin accessibility and gene expression in single cells. [PDF]
Nat Methods, 2022 Chen AF +5 more
europepmc +1 more source
Changes in Nuclear Basic Proteins During Pseudorabies Virus Infection [PDF]
, 1969 openalex +1 more source
Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source