Results 181 to 190 of about 8,612,670 (377)

Two well‐defined motifs in the cAMP‐dependent protein kinase inhibitor (PKIα) correlate with inhibitory and nuclear export function [PDF]

, 1999
Jennifer A. Hauer, Philippe Barthe, Susan S. Taylor, Joseph Parello, André Padilla   +4 more
openalex   +1 more source

Polyphosphate amplifies proinflammatory responses of nuclear proteins through interaction with receptor for advanced glycation end products and P2Y1 purinergic receptor.

Blood, 2014
P. Dinarvand, S. M. Hassanian, S. Qureshi, C. Manithody, J. C. Eissenberg, Likui Yang, A. Rezaie   +6 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The Nuclear Proteins TP73 and CUL4A Confer Resistance to Cytarabine by Induction of Translesion DNA Synthesis via Mono-ubiquitination of PCNA. [PDF]

Hemasphere, 2022
Rehberger M, Schäfer JA, Krampitz AM, Bretz AC, Jost L, Haferlach T, Stiewe T, Neubauer A.   +7 more
europepmc   +1 more source

The Conserved 12-Amino Acid Stretch in the Inter-Bromodomain Region of BET Family Proteins Functions as a Nuclear Localization Signal

, 2012
Hidesuke Fukazawa, Atsuko Masumi
openalex   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Oocyte Meiotic Competence in the Domestic Cat Model: Novel Roles for Nuclear Proteins BRD2 and NPM1. [PDF]

Front Cell Dev Biol, 2021
Chavez DR, Lee PC, Comizzoli P.
europepmc   +1 more source

Nuclear magnetic resonance detection and spectroscopy of single proteins using quantum logic

Science, 2016
I. Lovchinsky, A. Sushkov, E. Urbach, N. Leon, Soonwon Choi, K. D. Greve, R. Evans, Rona S. Gertner, E. Bersin, Christoph Müller, L. McGuinness, F. Jelezko, R. Walsworth, Hongkun Park, M. Lukin   +14 more
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Label-Free Quantitative Proteome Analysis Reveals the Underlying Mechanisms of Grain Nuclear Proteins Involved in Wheat Water-Deficit Response. [PDF]

Front Plant Sci, 2021
Li T, Zhu D, Han Z, Zhang J, Zhang M, Yan Y.   +5 more
europepmc   +1 more source