Results 51 to 60 of about 1,731,332 (381)
In vitro transport of a fluorescent nuclear protein and exclusion of non-nuclear proteins. [PDF]
The Journal of cell biology, 1986 An in vitro system was developed that provides a quick microscopic assay for nuclear transport. The assay uses an extract of Xenopus eggs, normal or synthetic nuclei, and a fluorescently labeled nuclear protein, nucleoplasmin. This in vitro system accurately mimics in vivo nuclear transport, both in exclusivity and in the amount of accumulation ...
Donald D. Newmeyer +2 more
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Sorting pathways of mitochondrial inner membrane proteins [PDF]
, 1990 Two distinct pathways of sorting and assembly of nuclear-encoded mitochondrial inner membrane proteins are described. In the first pathway, precursor proteins that carry amino-terminal targeting signals are initially translocated via contact sites ...
Hartl, Franz-Ulrich +5 more
core +2 more sources
Stem Cell Research, 2021 Emery-Dreifuss muscular dystrophy type 1 (EDMD1) is a rare genetic disease caused by mutations in the EMD gene coding for a nuclear envelope protein emerin.
Magdalena Machowska +4 more
doaj
Comparative genomics of nuclear envelope proteins
BMC Genomics, 2018 Background The nuclear envelope (NE) that encapsulates the nuclear genome is a double lipid bilayer with several integral and peripherally associated proteins.
Hita Sony Garapati, Krishnaveni Mishra
doaj +1 more source
Intracompartmental and Intercompartmental Transcriptional Networks Coordinate the Expression of Genes for Organellar Functions [PDF]
, 2011 Genes for mitochondrial and chloroplast proteins are distributed between the nuclear and organellar genomes. Organelle biogenesis and metabolism, therefore, require appropriate coordination of gene expression in the different compartments to ensure ...
Haberer, Georg +4 more
core +2 more sources
Nuclear proteins acting on mitochondria
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2011 An important mechanism in apoptotic regulation is changes in the subcellular distribution of pro- and anti-apoptotic proteins. Among the proteins that change in their localization and may promote apoptosis are nuclear proteins. Several of these nuclear proteins such as p53, Nur77, histone H1.2, and nucleophosmin were reported to accumulate in the ...
Lindenboim, Liora +2 more
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Medicago LINC complexes function in nuclear morphology, nuclear movement, and root nodule symbiosis 1[OPEN] [PDF]
, 2018 Nuclear movement is involved in cellular and developmental processes across eukaryotic life, often driven by Linker of Nucleoskeleton and Cytoskeleton (LINC) complexes, which bridge the nuclear envelope (NE) via the interaction of Klarsicht/ ANC-1/Syne-1
Cerro Sánchez, Pablo del +3 more
core +1 more source
Phylogenetic analysis of the SAP30 family of transcriptional regulators reveals functional divergence in the domain that binds the nuclear matrix [PDF]
, 2009 Background: Deacetylation of histones plays a fundamental role in gene silencing, and this is mediated by a corepressor complex containing Sin3 as an essential scaffold protein. In this report we examine the evolution of two proteins in this complex, the
Heinonen, TYK +3 more
core +3 more sources
Frontiers in Plant Science, 2014 Following the description of SAD1/UNC84 (SUN) domain proteins in higher plants, evidence has rapidly increased that plants contain a functional Linker of Nucleoskeleton and Cytoskeleton (LINC) complex bridging the nuclear envelope (NE).
David Edgar Evans +3 more
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source