Results 51 to 60 of about 8,399,803 (398)
Nuclear/Cytoplasmic Fractionation of Proteins from Caenorhabditis elegans [PDF]
, 2018 C. elegans is widely used to investigate biological processes related to health and disease. To study protein localization, fluorescently-tagged proteins can be used in vivo or immunohistochemistry can be performed in whole worms.
Mata Cabana, Alejandro +3 more
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Nuclear Lamins: Key Proteins for Embryonic Development
Biology, 2022 Lamins are essential components of the nuclear envelope and have been studied for decades due to their involvement in several devastating human diseases, the laminopathies.
Jasper Chrysolite Paul, Helena Fulka
doaj +1 more source
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
Nature Chemical Biology, 2013 N6-methyladenosine (m6A) is the most prevalent and reversible internal modification in mammalian messenger and non-coding RNAs. We report here that human METTL14 catalyzes m6A RNA methylation.
Jianzhao Liu +12 more
semanticscholar +1 more source
Phylogenetic analysis of the SAP30 family of transcriptional regulators reveals functional divergence in the domain that binds the nuclear matrix [PDF]
, 2009 Background: Deacetylation of histones plays a fundamental role in gene silencing, and this is mediated by a corepressor complex containing Sin3 as an essential scaffold protein. In this report we examine the evolution of two proteins in this complex, the
Heinonen, TYK +3 more
core +3 more sources
YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs
eLife, 2017 N6-methyladenosine (m6A) is the most abundant internal modification of eukaryotic messenger RNA (mRNA) and plays critical roles in RNA biology. The function of this modification is mediated by m6A-selective ‘reader’ proteins of the YTH family, which ...
I. A. Roundtree +12 more
semanticscholar +1 more source
Stem Cell Research, 2021 Emery-Dreifuss muscular dystrophy type 1 (EDMD1) is a rare genetic disease caused by mutations in the EMD gene coding for a nuclear envelope protein emerin.
Magdalena Machowska +4 more
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Nuclear variants of bone morphogenetic proteins
BMC Cell Biology, 2010 Background Bone morphogenetic proteins (BMPs) contribute to many different aspects of development including mesoderm formation, heart development, neurogenesis, skeletal development, and axis formation.
Meinhart Christopher A +8 more
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Sorting pathways of mitochondrial inner membrane proteins [PDF]
, 1990 Two distinct pathways of sorting and assembly of nuclear-encoded mitochondrial inner membrane proteins are described. In the first pathway, precursor proteins that carry amino-terminal targeting signals are initially translocated via contact sites ...
Hartl, Franz-Ulrich +5 more
core +2 more sources
GAPDH Mediates Nitrosylation of Nuclear Proteins
Nature Cell Biology, 2010 S-nitrosylation of proteins by nitric oxide is a major mode of signalling in cells. S-nitrosylation can mediate the regulation of a range of proteins, including prominent nuclear proteins, such as HDAC2 (ref. 2) and PARP1 (ref. 3). The high reactivity of
M. Kornberg +8 more
semanticscholar +1 more source
Comparative genomics of nuclear envelope proteins
BMC Genomics, 2018 Background The nuclear envelope (NE) that encapsulates the nuclear genome is a double lipid bilayer with several integral and peripherally associated proteins.
Hita Sony Garapati, Krishnaveni Mishra
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