Results 51 to 60 of about 8,612,670 (377)

The nuclear proteome of Trypanosoma brucei. [PDF]

open access: yesPLoS ONE, 2017
Trypanosoma brucei is a protozoan flagellate that is transmitted by tsetse flies into the mammalian bloodstream. The parasite has a huge impact on human health both directly by causing African sleeping sickness and indirectly, by infecting domestic ...
Carina Goos   +4 more
doaj   +1 more source

Regulation of alphaherpesvirus infections by the ICP0 family of proteins [PDF]

open access: yes, 2013
Immediate-early protein ICP0 of herpes simplex virus type 1 (HSV-1) is important for the regulation of lytic and latent viral infection. Like the related proteins expressed by other alphaherpesviruses, ICP0 has a zinc-stabilized RING finger domain that ...
Boutell, Chris, Everett, Roger
core   +1 more source

Functional Characterization of the Eukaryotic Cysteine Desulfurase Nfs1p from Saccharomyces cerevisiae [PDF]

open access: yes, 2004
Previous studies have indicated that the essential protein Nfs1 performs a crucial role in cellular iron-sulfur (Fe/S) protein maturation. The protein is located predominantly in mitochondria, yet low amounts are present in cytosol and nucleus.
Balk   +73 more
core   +3 more sources

Selection of specific and efficient siRNAs in new cellular model for Hutchinson-Gilford progeria syndrome therapy

open access: yesMolecular Therapy: Nucleic Acids
Hutchinson-Gilford progeria syndrome is a fatal genetic disorder caused by a point mutation in the gene encoding the nuclear envelope protein lamin A/C.
Volha Dzianisava   +3 more
doaj   +1 more source

Drosophila as a Model for Studying the Roles of Lamins in Normal Tissues and Laminopathies

open access: yesCells
Nuclear processes are fundamental to the regulation of cellular, tissue, and organismal function, especially in complex multicellular systems. Central to these processes are lamins and lamin-associated proteins, which contribute to nuclear structure ...
Aleksandra Zielińska   +3 more
doaj   +1 more source

Nuclear variants of bone morphogenetic proteins

open access: yesBMC Cell Biology, 2010
Background Bone morphogenetic proteins (BMPs) contribute to many different aspects of development including mesoderm formation, heart development, neurogenesis, skeletal development, and axis formation.
Meinhart Christopher A   +8 more
doaj   +1 more source

The gateway to chloroplast: re-defining the function of chloroplast receptor proteins [PDF]

open access: yes, 2012
Chloroplast biogenesis often requires a tight orchestration between gene expression (both plastidial and nuclear) and translocation of similar to 3000 nuclear-encoded proteins into the organelle.
Bölter, Bettina   +2 more
core   +1 more source

The protamine family of sperm nuclear proteins

open access: yesGenome Biology, 2007
SummaryThe protamines are a diverse family of small arginine-rich proteins that are synthesized in the late-stage spermatids of many animals and plants and bind to DNA, condensing the spermatid genome into a genetically inactive state.
R. Balhorn
semanticscholar   +1 more source

Comparative genomics of nuclear envelope proteins

open access: yesBMC Genomics, 2018
Background The nuclear envelope (NE) that encapsulates the nuclear genome is a double lipid bilayer with several integral and peripherally associated proteins.
Hita Sony Garapati, Krishnaveni Mishra
doaj   +1 more source

Role of the unique N-terminal domain of CtBP2 in determining the subcellular localisation of CtBP family proteins [PDF]

open access: yes, 2006
BACKGROUND: CtBP1 and CtBP2 are transcriptional co-repressors that modulate the activity of a large number of transcriptional repressors via the recruitment of chromatin modifiers.
Bergman, Lee M.   +5 more
core   +2 more sources

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