Results 41 to 50 of about 1,706,990 (206)

The role of Schizosaccharomyces pombe SUMO ligases in genome stability [PDF]

, 2007
SUMOylation is a post-translational modification that affects a large number of proteins, many of which are nuclear. While the role of SUMOylation is beginning to be elucidated, it is clear that understanding the mechanisms that regulate the process is ...
A. Skilton, al-Khodairy, Allshire, Allshire, Andrews, Apionishev, Branzei, Chakrabarti, Cheng, E.A. Outwin, Ekwall, F.-X. Ogi, F.Z. Watts, Grishchuk, Ho, Ho, Hoege, Hooker, J.C.-Y. Ho, Johnson, Kagey, Kahyo, L. Gardner, L.K. Boyd, M.A.M. Trickey, McDonald, Okubo, Pichler, Potts, Reindle, Sachdev, Schmidt, Sergeant, Shayeghi, Shin, Stelter, Strahl-Bolsinger, Tanaka, Taylor, Thon, Watts, Xhemalce, Xhemalce, Zhao, Zhao   +44 more
core   +2 more sources

Selection of specific and efficient siRNAs in new cellular model for Hutchinson-Gilford progeria syndrome therapy

Molecular Therapy: Nucleic Acids
Hutchinson-Gilford progeria syndrome is a fatal genetic disorder caused by a point mutation in the gene encoding the nuclear envelope protein lamin A/C.
Volha Dzianisava, Katarzyna Piekarowicz, Magdalena Machowska, Ryszard Rzepecki   +3 more
doaj   +1 more source

Contact sites between inner and outer membranes [PDF]

, 1990
Contact sites between both mitochondrial membranes play a predominant role in the transport of nuclear-coded precursor proteins into mitochondria. The characterization of contact sites was greatly advanced by the reversible accumulation of precursor ...
Attardi, Chen, Dumont, Eilers, Hackenbrock, Hartl, Hartl, Hartl, Hawlitschek, Hurt, Kellems, Nargang, Nicholson, Ostermann, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pon, Rassow, Rosenberg, Schleyer, Schwaiger, Stuart, Sztul, Söllner, Söllner, Vestweber   +30 more
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Drosophila as a Model for Studying the Roles of Lamins in Normal Tissues and Laminopathies

Cells
Nuclear processes are fundamental to the regulation of cellular, tissue, and organismal function, especially in complex multicellular systems. Central to these processes are lamins and lamin-associated proteins, which contribute to nuclear structure ...
Aleksandra Zielińska, Marta Rowińska, Aleksandra Tomczak, Ryszard Rzepecki   +3 more
doaj   +1 more source

Nuclear variants of bone morphogenetic proteins

BMC Cell Biology, 2010
Background Bone morphogenetic proteins (BMPs) contribute to many different aspects of development including mesoderm formation, heart development, neurogenesis, skeletal development, and axis formation.
Meinhart Christopher A, Gaufin Stephanie L, Sperry Daniel K, Jensen J Daniel, Loos Trina J, Mayo Jaime L, Felin Jenny E, Moss Jennie B, Bridgewater Laura C   +8 more
doaj   +1 more source

Comparative genomics of nuclear envelope proteins

BMC Genomics, 2018
Background The nuclear envelope (NE) that encapsulates the nuclear genome is a double lipid bilayer with several integral and peripherally associated proteins.
Hita Sony Garapati, Krishnaveni Mishra
doaj   +1 more source

The protein import apparatus of chloroplasts [PDF]

, 1993
Routing of cytosolically synthesized precursor proteins into chloroplasts is a specific process which involves a multitude of soluble and membrane components.
Bartling D., Bassham D. C., Buvinger W. E., Cline K., Cline K., Cline K., Heike Alefsen, Joyard J., Jürgen Soll, Kirwin P. M., Li H.‐M., Mould R. M., Olsen L. J., Olsen L. J., Perry S. E., Pilon M., Schnell D. J., Theg S. M.   +17 more
core   +1 more source

Protein interactions at the higher plant nuclear envelope: evidence for a Linker of Nucleoskeleton and Cytoskeleton complex.

Frontiers in Plant Science, 2014
Following the description of SAD1/UNC84 (SUN) domain proteins in higher plants, evidence has rapidly increased that plants contain a functional Linker of Nucleoskeleton and Cytoskeleton (LINC) complex bridging the nuclear envelope (NE).
David Edgar Evans, Vidya ePawar, Sarah Jane Smith, Katja eGraumann   +3 more
doaj   +1 more source

SUN/KASH interactions facilitate force transmission across the nuclear envelope. [PDF]

, 2019
LINC complexes (Linker of Nucleoskeleton and Cytoskeleton), consisting of inner nuclear membrane SUN (Sad1, UNC-84) proteins and outer nuclear membrane KASH (Klarsicht, ANC-1, and Syne Homology) proteins, are essential for nuclear positioning, cell ...
Hao, Hongyan, Starr, Daniel A
core  

Nuclear Resonance Vibrational Spectroscopy of Iron Sulfur Proteins

, 2012
Nuclear inelastic scattering in conjunction with density functional theory (DFT) calculations has been applied for the identification of vibrational modes of the high-spin ferric and the high-spin ferrous iron-sulfur center of a rubredoxin-type protein ...
A. I. Chumakov, A. X. Trautwein, A.J.H. Wachters, B. Miehlich, C. Lee, C. Schmidt, H. Paulsen, H. Winkler, M.J. Frisch, P. Wegner, P. Wegner, P.J. Hay, R. Rüffer, R.S. Czernuszewicz, T.G. Spiro, T.R. Cundari, U. Bergmann, V. Schünemann, V. Schünemann, W.J. Stevens   +19 more
core   +1 more source