Results 61 to 70 of about 12,222,224 (337)

Comparative genomics of nuclear envelope proteins

BMC Genomics, 2018
Background The nuclear envelope (NE) that encapsulates the nuclear genome is a double lipid bilayer with several integral and peripherally associated proteins.
Hita Sony Garapati, Krishnaveni Mishra
doaj   +1 more source

GAPDH Mediates Nitrosylation of Nuclear Proteins

Nature Cell Biology, 2010
S-nitrosylation of proteins by nitric oxide is a major mode of signalling in cells. S-nitrosylation can mediate the regulation of a range of proteins, including prominent nuclear proteins, such as HDAC2 (ref. 2) and PARP1 (ref. 3). The high reactivity of
M. Kornberg, Nilkantha Sen, Makoto R. Hara, K. Juluri, Judy Van K Nguyen, A. Snowman, Lindsey Law, L. Hester, S. Snyder   +8 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Protein interactions at the higher plant nuclear envelope: evidence for a Linker of Nucleoskeleton and Cytoskeleton complex.

Frontiers in Plant Science, 2014
Following the description of SAD1/UNC84 (SUN) domain proteins in higher plants, evidence has rapidly increased that plants contain a functional Linker of Nucleoskeleton and Cytoskeleton (LINC) complex bridging the nuclear envelope (NE).
David Edgar Evans, Vidya ePawar, Sarah Jane Smith, Katja eGraumann   +3 more
doaj   +1 more source

Nuclear magnetic resonance [PDF]

, 2012
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166This article reviews the principles and methods of nuclear magnetic resonance spectroscopy, and gives examples of applications carried out at our Facility, which illustrate the ...
Molins i Montserrat, Mª Antònia, Gairí Tahull, Margarida, Muñoz-Torrero López-Ibarra, Victoria, Gonzalez, Teresa, Feliz Rodenas, Miguel   +4 more
core   +5 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Farnesylated Nuclear Proteins Kugelkern and Lamin Dm0 Affect Nuclear Morphology by Directly Interacting with the Nuclear Membrane

Molecular Biology of the Cell, 2010
Nuclear shape changes are observed during a variety of developmental processes, pathological conditions and ageing. Here, the molecular mechanism is analyzed how the farnesylated nuclear proteins interact with the nuclear envelope and deform the ...
Maria Polychronidou, A. Hellwig, J. Grosshans   +2 more
semanticscholar   +1 more source

The role of emerin and LEM domain proteins in nuclear envelope assembly and cytoskeleton organisation [PDF]

, 2005
The nuclear envelope (NE) plays a fundamental role in the cell by separating nuclear from cytoplasmic activities, and mutations in NE proteins have been associated with a diverse array of diseases.
Saipingidou, Georgia, Salpingidou, Georgia   +1 more
core  

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Nuclear Lamins: Key Proteins for Embryonic Development

Biology, 2022
Lamins are essential components of the nuclear envelope and have been studied for decades due to their involvement in several devastating human diseases, the laminopathies.
Jasper Chrysolite Paul, Helena Fulka
doaj   +1 more source