Results 211 to 220 of about 1,210,728 (258)

Unraveling PPARβ/δ nuclear receptor agonists <i>via</i> a drug-repurposing approach: HTVS-based ligand identification, molecular dynamics, pharmacokinetics, and <i>in vitro</i> anti-steatotic validation. [PDF]

RSC Adv
Mandal SK, Muzaffar-Ur-Rehman M, Puri S, Kumar BK, Sharma PK, Sankaranarayanan M, Deepa PR.   +6 more
europepmc   +1 more source

Nuclear receptor 4A1 Regulates Mitochondrial Homeostasis in Cardiac Post-Ischemic Injury by Controlling Mitochondrial Fission 1 Protein-Mediated Fragmentation and Parkin-Dependent Mitophagy. [PDF]

Int J Biol Sci
Ye H, Lin J, Zhang H, Wang J, Fu Y, Zeng Z, Zheng J, Tao J, Qiu J.   +8 more
europepmc   +1 more source

Nuclear receptor corepressors non-canonically drive glucocorticoid receptor-dependent activation of hepatic gluconeogenesis. [PDF]

Nat Metab
Hauck AK, Mehmood R, Carpenter BJ, Frankfurter MT, Tackenberg MC, Inoue SI, Krieg MK, Cassim Bawa FN, Midha MK, Zundell DM, Batmanov K, Lazar MA.   +11 more
europepmc   +1 more source

SUMOylation of nuclear receptor Nor1/NR4A3 coordinates microtubule cytoskeletal dynamics and stability in neuronal cells. [PDF]

Cell Biosci
Gagnon J, Caron V, Tremblay A.
europepmc   +1 more source

p160 nuclear receptor coactivator family members and their role in rare fusion‑driven neoplasms (Review). [PDF]

Oncol Lett
Segovia D, Tepes PS.
europepmc   +1 more source

Magnetic resonance imaging evaluation and nuclear receptor binding SET domain protein 1 mutation in the Sotos syndrome with attention-deficit/hyperactivity disorder.

World J Clin Cases
Zhu W.
europepmc   +1 more source

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Bioinformatics of Nuclear Receptors

2003
Publisher Summary This chapter reviews the information that biologists interested in nuclear receptors can get by using a computer, including general resources and those specialized in nuclear receptors, whether for accessing data or analyzing it.
Marc Robinson-Rechavi, Vincent Laudet
openaire   +6 more sources

Nuclear receptor coactivators

Current Opinion in Cell Biology, 1997
Retinoic acid, steroid and thyroid hormones regulate complex programs of gene expression by binding to intracellular receptors that are members of the nuclear receptor superfamily of ligand-dependent transcription factors. Recent studies have led to the identification and cloning of genes encoding coactivator molecules that appear to play important ...
Michael G. Rosenfeld, David W. Rose, Christopher K. Glass   +2 more
openaire   +2 more sources

Oxysterols and nuclear receptors

Molecular and Cellular Endocrinology, 2019
Oxysterols are derivatives of cholesterol and an important regulator of cholesterol metabolism, in part due to their role as ligands for nuclear receptors, such as the liver X receptors. Oxysterols are also known to be ligands for the RAR-related orphan receptors, involved in normal T cell differentiation.
Liqian Ma, Erik R. Nelson
openaire   +3 more sources