Results 231 to 240 of about 1,364,815 (358)

Orphan Nuclear Receptor NR4A1 Promotes Proliferation and Osteogenic Differentiation of Valvular Interstitial Cells through Activation of CCND2. [PDF]

Int J Biol Sci
Shen Q, Zhang C, Jiang C, Liu Z, Fan L, Luo H, Qian X, Fan Z, Yao D, Dong N, Shi J.   +10 more
europepmc   +1 more source

Role of the nuclear pregnane X receptor in drug metabolism and the clinical response

, 2015

openalex   +1 more source

TR4 nuclear receptor enhances prostate cancer initiation via altering the stem cell population and EMT signals in the PPARG-deleted prostate cells [PDF]

, 2015
Shin-Jen Lin, Dong-Rong Yang, Nancy Wang, Ming Jiang, Hiroshi Miyamoto, Gonghui Li, Chawnshang Chang   +6 more
openalex   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

The nuclear receptor NR6A1 plays an oncogenic role through reprogramming glycolysis in tumors. [PDF]

Biol Res
Liu X, Li Y, Rao X, Xie S, Rong Z, Yang L, Mao ZE, Li D.   +7 more
europepmc   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Potential endogenous lipid ligands for the nuclear receptor transcription factor Steroidogenic Factor-1. [PDF]

Adv Biol Regul
Campbell AN, Blind RD.
europepmc   +1 more source

Nuclear Receptors [PDF]

Cell, 2003
Belandia, Borja, Parker, Malcolm G.
openaire   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Nuclear receptor co-factor TBL1X/TBL1XR1 T cell activity protects against atherosclerosis. [PDF]

Mol Metab
Cingir Koker S, Mhamane A, Geppert J, Shakir G, Guillamat-Prats R, Chen B, Katra P, Geiger M, Tsokanos FF, Wolff G, Szendrödi J, Rohm M, Daniel C, Maegdefessel L, Steffens S, Herzig S.   +15 more
europepmc   +1 more source