Results 161 to 170 of about 881,535 (329)

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Transcriptional Control by Nuclear Steroid Hormone Receptors

, 2000
Shigcaki Kato
openalex   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Effect of Puerarin on Chronic Alcoholic Encephalopathy by Modulating the “Microbiota‐Gut‐Brain Axis” Lipopolysaccharides/Toll‐Like Receptors 4/Nuclear Factor Kappa‐B Inflammatory Pathway [PDF]

Lei Zhang, Bo Li, Fa Ye, Lin Zi Li, Shan Xiong, Shan Shan Lei   +5 more
openalex   +1 more source

Minireview: Regulation of Gap Junction Dynamics by Nuclear Hormone Receptors and Their Ligands [PDF]

, 2012
Gary L. Firestone, Bhumika J. Kapadia
openalex   +1 more source

Supplementary Figure 11 from A Comprehensive View of Nuclear Receptor Cancer Cistromes

, 2023
Qianzi Tang, Yiwen Chen, Clifford A. Meyer, Tim Geistlinger, Mathieu Lupien, Qian Wang, Tao Liu, Yong Zhang, Myles Brown, Xiaole Shirley Liu   +9 more
openalex   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Nuclear Factor-κB Activates Transcription of the Androgen Receptor Gene in Sertoli Cells Isolated from Testes of Adult Rats [PDF]

, 2003
Liying Zhang, Martin Charron, William W. Wright, Bandana Chatterjee, Chung S. Song, Arun K. Roy, Terry R. Brown   +6 more
openalex   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Nuclear Receptor [PDF]

, 2020
openaire   +1 more source