Results 21 to 30 of about 6,546,541 (274)

Both Nuclear Size and DNA Amount Contribute to Midblastula Transition Timing in Xenopus laevis [PDF]

Scientific Reports, 2017
During early Xenopus laevis embryogenesis both nuclear and cell volumes decrease with the nuclear-to-cytoplasmic (N/C) volume ratio reaching a maximum at the midblastula transition (MBT). At the MBT, embryonic transcription is upregulated and cell cycles
Predrag Jevtić, Daniel L. Levy
doaj   +2 more sources

The Perinuclear ER Scales Nuclear Size Independently of Cell Size in Early Embryos. [PDF]

Dev Cell, 2020
Mukherjee RN, Sallé J, Dmitrieff S, Nelson KM, Oakey J, Minc N, Levy DL.   +6 more
europepmc   +2 more sources

Cell biology: Import and nuclear size. [PDF]

Nature, 2010
Cohen-Fix O.
europepmc   +3 more sources

Region-specific heterogeneity in neuronal nuclear morphology in young, aged and in Alzheimer’s disease mouse brains

Frontiers in Cell and Developmental Biology, 2023
Neurons in the mammalian brain exhibit enormous structural and functional diversity across different brain regions. Compared to our understanding of the morphological diversity of neurons, very little is known about the heterogeneity of neuronal nuclear ...
Soumen Das, Narendrakumar Ramanan
doaj   +1 more source

Spindle Architectural Features Must Be Considered Along With Cell Size to Explain the Timing of Mitotic Checkpoint Silencing

Frontiers in Physiology, 2021
Mitosis proceeds through a defined series of events that is largely conserved, but the amount of time needed for their completion can vary in different cells and organisms.
Mathew Bloomfield, Jing Chen, Daniela Cimini   +2 more
doaj   +1 more source

Discovery of a Novel Aminocyclopropenone Compound That Inhibits BRD4-Driven Nucleoporin NUP210 Expression and Attenuates Colorectal Cancer Growth

Cells, 2022
Epigenetic deregulation plays an essential role in colorectal cancer progression. Bromodomains are epigenetic “readers” of histone acetylation. Bromodomain-containing protein 4 (BRD4) plays a pivotal role in transcriptional regulation and is a feasible ...
Hiroya Kondo, Kenji Mishiro, Yuki Iwashima, Yujia Qiu, Akiko Kobayashi, Keesiang Lim, Takahiro Domoto, Toshinari Minamoto, Kazuma Ogawa, Munetaka Kunishima, Masaharu Hazawa, Richard W. Wong   +11 more
doaj   +1 more source

The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity. [PDF]

EMBO Rep, 2019
Jevtić P, Schibler AC, Wesley CC, Pegoraro G, Misteli T, Levy DL.   +5 more
europepmc   +2 more sources

Recent advances in understanding nuclear size and shape. [PDF]

Nucleus, 2016
Mukherjee RN, Chen P, Levy DL.
europepmc   +2 more sources

Sizing up the nucleus: nuclear shape, size and nuclear-envelope assembly [PDF]

Journal of Cell Science, 2009
The nucleus is one of the most prominent cellular organelles, yet surprisingly little is known about how it is formed, what determines its shape and what defines its size. As the nuclear envelope (NE) disassembles in each and every cell cycle in metazoans, the process of rebuilding the nucleus is crucial for proper development and cell proliferation ...
Micah, Webster, Keren L, Witkin, Orna, Cohen-Fix   +2 more
openaire   +2 more sources

Nuclear sizes and the isotope shift [PDF]

Physical Review A, 1997
Darwin-Foldy nuclear-size corrections in electronic atoms and nuclear radii are discussed from the nuclear-physics perspective. Interpretation of precise isotope-shift measurements is formalism dependent, and care must be exercised in interpreting these results and those obtained from relativistic electron scattering from nuclei.
Friar, J. L., Martorell Domenech, Juan, Sprung, Donald W. L.   +2 more
openaire   +3 more sources