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Editing the CYP19 Gene in Goat Embryos Using CRISPR/Cas9 and Somatic Cell Nuclear Transfer Techniques

Cellular Reprogramming
The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas9) system is revolutionizing genome engineering and is expected to bring significant advancements in livestock traits, including the treatment of genetic diseases. This study focuses on CRISPR/Cas9-mediated modifications of the CYP19 gene, which encodes aromatase, an enzyme ...
Ahmad Pirali   +12 more
openaire   +2 more sources

Development of somatic cell nuclear transfer technique for biomedical and agricultural research (year II) : report

2005
There are two objectives of the somatic nuclear transfer studies. The first objective was to evaluate the possibility to produce the inter-species cloned embryos from donor cells of different animals transfer to rabbit, pig or swamp buffalo oocytes. The second objective was to study the donor cell type can significantly affect the in vitro development ...
Mongkol Techakumphu   +5 more
openaire   +1 more source

A novel gene-transfer technique mediated by HVJ (Sendai virus), nuclear protein, and liposomes.

Cancer detection and prevention, 1995
There have been many reports of in vivo direct gene transfer methods, but there are problems with these methods. Recently, we developed a novel, nontoxic and efficient in vivo direct gene transfer method mediated by Sendai virus (HVJ) and liposomes. In our system, foreign genes and nuclear proteins were encapsulated into the same liposomes, which were ...
N, Tomita   +4 more
openaire   +1 more source

A promising nuclear transfer technique for repairing aged oocytes

Fertility and Sterility, 2010
A. Tanaka   +5 more
openaire   +1 more source

Production of transgenic goats expressing human coagulation factor IX in the mammary glands after nuclear transfer using transfected fetal fibroblast cells

Transgenic research, 2013
Amir Amiri Yekta   +17 more
semanticscholar   +1 more source

Transfer Learning Technique Using Similar Phenomena Training for Fuel Digital Twins of Nuclear Systems

13th Nuclear Plant Instrumentation, Control & Human-Machine Interface Technologies (NPIC&HMIT 2023), 2023
James Daniell   +4 more
openaire   +1 more source

Production of transgenic and knockout pigs by somatic cell nuclear transfer.

Methods in molecular biology, 2012
A. Giraldo, S. Ball, K. Bondioli
semanticscholar   +1 more source

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