Results 41 to 50 of about 713,586 (294)
Pharmaceutical Biology, 2018 Context: Polypropylenimine (PPI), a cationic dendrimer with defined structure and positive surface charge, is a potent non-viral vector. Dexamethasone (Dexa) conveys to the nucleus through interaction with its intracellular receptor.
Bizhan Malaekeh-Nikouei +4 more
doaj +1 more source
Mitochondrial transfer: Ethical legal and social implications in assisted reproduction
South African Journal of Bioethics and Law, 2015 Diseases resulting from mutations in mitochondrial DNA (mtDNA) are inherited by all offspring through the maternal lineage. Multiple organs, which require high cellular energy production, are severely affected.
Alexandra Reznichenko +2 more
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Advances in passive heat transfer enhancement for heat exchangers a comprehensive review
Journal of Thermal EngineeringThis paper reviews the latest advances in passive heat transfer enhancement techniques, ad-dressing the gap in the literature regarding recent developments.
Muhammad Ali KHAN +4 more
doaj +1 more source
Quantitative CEST imaging of amide proton transfer in acute ischaemic stroke
NeuroImage: Clinical, 2019 Background: Amide proton transfer (APT) imaging may help identify the ischaemic penumbra in stroke patients, the classical definition of which is a region of tissue around the ischaemic core that is hypoperfused and metabolically stressed.
Y. Msayib +8 more
doaj +1 more source
Conversion from Film to Image Plates for Transfer Method Neutron Radiography of Nuclear Fuel
, 2017 This paper summarizes efforts to characterize and qualify a computed radiography (CR) system for neutron radiography of irradiated nuclear fuel at Idaho National Laboratory (INL).
A. Craft +3 more
semanticscholar +1 more source
Toward dynamic structural biology: Two decades of single-molecule Förster resonance energy transfer
Science, 2018 Watching single molecules in motion Structural techniques such as x-ray crystallography and electron microscopy give insight into how macromolecules function by providing snapshots of different conformational states.
Eitan Lerner +6 more
semanticscholar +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Heat Transfer in Cavities: Configurative Systematic Review
Energies, 2023 This study is a systematic review of research on heat transfer analysis in cavities and aims to provide a comprehensive understanding of flow and heat transfer performance in various kinds of cavities with or without the presence of fins, obstacles ...
Goutam Saha +3 more
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