Results 31 to 40 of about 146,303 (307)

Nuclear transfer technique affects mRNA abundance, developmental competence and cell fate of the reconstituted sheep oocytes [PDF]

open access: yesReproduction, 2013
Abstract The effect of technical steps of somatic cell nuclear transfer (SCNT) on different aspects of cloned embryo development was investigated in sheep. In vitro-matured oocytes were enucleated in the presence or absence of zona and reconstituted by three different SCNT techniques: conventional zona-intact (ZI-NT), standard zona ...
F, Moulavi   +7 more
openaire   +2 more sources

A Review of the Uses of Nuclear Radiation in Tobacco and Smoke Research

open access: yesContributions to Tobacco and Nicotine Research, 1990
In summary, nuclear radiation has been widely used to elucidate many aspects of the mechanisms of tobacco being converted to smoke. In addition, the mechanisms of smoke transfer, tobacco inorganic chemistry and smoke filtration have been clarified by ...
Jenkins RW
doaj   +1 more source

Nuclear reprogramming: kinetics of cell cycle and metabolic progression as determinants of success

open access: yes, 2012
Establishment of totipotency after somatic cell nuclear transfer (NT) requires not only reprogramming of gene expression, but also conversion of the cell cycle from quiescence to the precisely timed sequence of embryonic cleavage.
Franchesca Dawn Houghton (171722)   +44 more
core   +1 more source

Radia2: A New Tool for Radiotherapy Verification [PDF]

open access: yes, 2013
Radiotherapy is nowadays a proven technique in cancer treatments. Within the evolution of radiotherapy treatments towards more complex techniques, the need of new dosimetric methods for treatment verifications has appeared.
Gallardo Fuentes, María Isabel   +9 more
core   +1 more source

Synthesis, characterization and evaluation of transfection efficiency of dexamethasone conjugated poly(propyleneimine) nanocarriers for gene delivery#

open access: yesPharmaceutical Biology, 2018
Context: Polypropylenimine (PPI), a cationic dendrimer with defined structure and positive surface charge, is a potent non-viral vector. Dexamethasone (Dexa) conveys to the nucleus through interaction with its intracellular receptor.
Bizhan Malaekeh-Nikouei   +4 more
doaj   +1 more source

Mitochondrial transfer: Ethical legal and social implications in assisted reproduction

open access: yesSouth African Journal of Bioethics and Law, 2015
Diseases resulting from mutations in mitochondrial DNA (mtDNA) are inherited by all offspring through the maternal lineage. Multiple organs, which require high cellular energy production, are severely affected.
Alexandra Reznichenko   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Quantitative CEST imaging of amide proton transfer in acute ischaemic stroke

open access: yesNeuroImage: Clinical, 2019
Background: Amide proton transfer (APT) imaging may help identify the ischaemic penumbra in stroke patients, the classical definition of which is a region of tissue around the ischaemic core that is hypoperfused and metabolically stressed.
Y. Msayib   +8 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Influence of Neighbouring Clouds on the Clear Sky Reflectance Studied with the 3-D Transport Code RADUGA

open access: yes, 2005
Operational remote sensing of terrestrial atmosphere is heavily based on the 1-D radiative transfer equation. However, cloudy scenes are influenced by 3-D effects (e.g., illumination from cloud sides, etc.).
Nikolaeva, O.V.   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy