Results 71 to 80 of about 624,823 (322)

Cryopreservation of Avian Germline Cells and Subsequent Production of Viable Offspring

The Journal of Poultry Science, 2003
Cryopreservation of avian genetic material has become possible by preserving blastodermal cells or primordial germ cells. These germline cells can give rise to viable offspring via germline chimaeras.
Mitsuru Naito
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Recent State and Challenges in Spectroelectrochemistry with Its Applications in Microfluidics

Micromachines, 2023
This review paper presents the recent developments in spectroelectrochemical (SEC) technologies. The coupling of spectroscopy and electrochemistry enables SEC to do a detailed and comprehensive study of the electron transfer kinetics and vibrational ...
Zhenglong Li, Charmi Chande, Yu-Hsuan Cheng, Sagnik Basuray   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Design and Analysis of Nuclear Transportation Cask Using Phase Changing Material

Tehnički Glasnik
In the nuclear sector, secure transportation of radioactive materials is crucial in the nuclear sector, and cask design and analysis are crucial for maintaining fuel integrity.
Girish Venkatesh Gudi, R. G. Nagraj, Abhijit Dandavate   +2 more
doaj   +1 more source

Glycosaminoglycan-Protein Interactions by Nuclear Magnetic Resonance (NMR) Spectroscopy

Molecules, 2018
Nuclear magnetic resonance (NMR) spectroscopy is one of the most utilized and informative analytical techniques for investigating glycosaminoglycan (GAG)-protein complexes.
Vitor H. Pomin, Xu Wang
doaj   +1 more source

Cooper pair transfer in nuclei

, 2013
The second order DWBA implementation of two-particle transfer direct reactions which includes simultaneous and successive transfer, properly corrected by non-orthogonality effects is tested with the help of controlled nuclear structure and reaction ...
Barranco, F., Broglia, R. A., Idini, A., Potel, G., Vigezzi, E.   +4 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Experimental investigation on heat transfer characteristics of a novel hypervapotron channel for divertor target in nuclear fusion reactors

Nuclear Materials and Energy
In the further development of nuclear fusion energy, managing the high heat flux on a divertor target remains a significant issue. To address this, the development of innovative cooling channels capable of efficiently managing high heat loads is ...
Zhen Chen, Qiang Li, Zhanru Zhou, Xingli Wang, Bowen Zhao, Wuqingliang Peng, Fangyong Du, Wanjing Wang, Zhongshi Yang, Yuping Xu, Shenghong Huang, Haishan Zhou, Guang-Nan Luo   +12 more
doaj   +1 more source

Ethical issues of human cloning

Journal of Medical Sciences, 2020
Cloning can help us in the research field and medical sciences. But due to ethical and moral values, this idea is not supported. Moreover, it is against ethical values as well.
Nasrullah, Rana Khalid Iqbal, Shahzadi BiBi, Sana Muneer, Sumaira BiBi, Farhana Naureen Anwar   +5 more
doaj   +1 more source